Document Detail

Comparison of angiogenic and anti-angiogenic factors in maternal and umbilical cord blood in early- and late-onset pre-eclampsia.
MedLine Citation:
PMID:  22429154     Owner:  NLM     Status:  Publisher    
Purpose: The aim of this study was to compare maternal and umbilical cord serum levels of the angiogenic and anti-angiogenic factors in early- and late-onset pre-eclamptic pregnancies as well as in normal pregnancies, which might have significant importance in the etiology of pre-eclampsia. Materials and Methods: This prospective case-control study was carried out with pre-eclamptic (early-onset, ≤ 34 weeks and late-onset, >34 weeks) and normal pregnant women. VEGF, PIGF, sFlt-1 and sEng levels in maternal and umbilical cord serum were measured before delivery and the findings were compared. Results: The study was conducted with 15 early- and 15 late-onset pre-eclampsia patients, and 17 patients with normal pregnancies. It was found that sEng levels were higher in the umbilical cord serum in the early-onset and in the maternal serum in the late-onset pre-eclampsia group than the control group (p < 0.05). No significant difference in any factor was observed between the early- and late-onset pre-eclampsia groups. Conclusion: In this study, the results showed that angiogenic and anti-angiogenic factor levels in maternal serum and umbilical cord serum may not be related to the time of onset of pre-eclampsia.
Selda Demircan Sezer; Mert Küçük; Ciğdem Yenisey; Hasan Yüksel; Ali Rıza Odabaşı; Münevver Kaynak Türkmen; Bilin Çetinkaya Cakmak; Imran Kurt Omürlü
Related Documents :
14709184 - Sexual trauma and pregnancy: a conceptual framework.
2511514 - Support of the pregnant soldier in the workplace: a comparison of her assessment with t...
7965194 - Clues to positive birth outcomes in new mexico.
22019614 - Lack of association between endogenous lh and pregnancy in gnrh antagonist protocols.
2763994 - Parity as a risk factor for cervical cancer.
2110074 - Risk of a second consecutive first-trimester spontaneous abortion in women who conceive...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-20
Journal Detail:
Title:  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology     Volume:  -     ISSN:  1473-0766     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807913     Medline TA:  Gynecol Endocrinol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Obstetrics and Gynecology, Adnan Menderes University , Faculty of Medicine, Aydın , Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Reduction of Listeria monocytogenes and spoilage bacteria on smoked catfish using X-ray treatments.
Next Document:  Gastrointestinal disease outbreak detection using multiple data streams from electronic medical reco...