Document Detail

Comparison of anesthetic efficacy of 4% articaine and 2% lidocaine for maxillary buccal infiltration in patients with irreversible pulpitis.
MedLine Citation:
PMID:  19101495     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this prospective, randomized, double-blind study was to compare the anesthetic efficacy of 4% articaine and 2% lidocaine (both with 1:100,000 epinephrine) for buccal infiltration in patients experiencing irreversible pulpitis in maxillary posterior teeth. STUDY DESIGN: Forty patients with irreversible pulpitis in first premolar or first molar were divided into 4 study groups and received buccal infiltration of either 4% articaine or 2% lidocaine in a double-blind manner. Endodontic access was begun 5 minutes after solution deposition. Success was defined as no or mild discomfort (VAS recordings) during the endodontic procedure. RESULTS: The success rate for maxillary buccal infiltration to produce pulpal anesthesia using articaine was 100% in first premolar and first molar, and for the lidocaine solution, success rate was 80% in first premolar and 30% in first molar. There was high significant difference between the articaine and lidocaine solutions (ANOVA; P < .001). CONCLUSION: The efficacy of 4% articaine was superior to 2% lidocaine for maxillary buccal infiltration in posterior teeth.
Narasimhan Srinivasan; Mahendran Kavitha; Chandarasekaran S Loganathan; Govindasamy Padmini
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  107     ISSN:  1528-395X     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-22     Completed Date:  2009-02-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  133-6     Citation Subset:  D; IM    
Department of Conservative Dentistry, Tamilnadu Government Dental College and Hospital, Chennai-3, India.
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MeSH Terms
Anesthesia, Dental / methods*
Anesthesia, Local / methods*
Anesthetics, Local / administration & dosage*
Carticaine / administration & dosage*
Double-Blind Method
Lidocaine / administration & dosage*
Pain Measurement
Prospective Studies
Pulpitis / therapy*
Root Canal Therapy*
Young Adult
Reg. No./Substance:
0/Anesthetics, Local; 137-58-6/Lidocaine; 23964-58-1/Carticaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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