| Comparison of anastomotic microcirculation in coloanal J-pouches versus straight and side-to-end coloanal reconstruction: an experimental study in the pig. | |
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MedLine Citation:
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PMID: 10855555 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Several studies have shown a lower rate of anastomotic leakages in patients with coloanal J-pouch reconstruction than in those with straight coloanal anastomosis following anterior resection of the rectum. This study investigated whether this difference is due to a better anastomotic microcirculation. Thirty-two healthy, adult Göttinger mini-pigs underwent anterior rectal resection. They were subsequently randomized to following four groups (eight pigs per group): straight end-to-end, side-to-end, small pouch (4 cm), and large pouch (8 cm) coloanal anastomosis. Bowel perfusion was measured before and after vessel ligature at predefined locations using laser Doppler flowmetry. After completion of the anastomosis microcirculation was investigated 1 cm above, below, and directly at the anastomotic site. Following vessel ligature there was a 25% drop in blood flow. After completion of the anastomosis there was a further decrease of 25% in the distal segment, while no changes were observed above the anastomosis. There were no statistical differences either before or after completion of the anastomosis between the various groups. It is concluded that anastomotic blood flow does not depend on the type of coloanal reconstruction in healthy pigs. |
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Authors:
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M Sailer; E S Debus; K H Fuchs; J Beyerlein; A Thiede |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: International journal of colorectal disease Volume: 15 ISSN: 0179-1958 ISO Abbreviation: Int J Colorectal Dis Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-10-05 Completed Date: 2000-10-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8607899 Medline TA: Int J Colorectal Dis Country: GERMANY |
Other Details:
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Languages: eng Pagination: 114-7 Citation Subset: IM |
Affiliation:
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Chirurgische Klinik und Poliklinik, Universität Würzburg, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anastomosis, Surgical
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methods* Animals Colon / blood supply, surgery* Laser-Doppler Flowmetry Microcirculation / physiology Proctocolectomy, Restorative* Swine |
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