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Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: A meta-analysis of randomized controlled trials.
MedLine Citation:
PMID:  22154987     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: Given that previous studies have reached conflicting conclusions regarding the effects of diet (D), aerobic exercise (E) or both (DE) on blood lipid and lipoprotein concentrations in adults, the meta-analytic approach was used to address this issue. DATA SOURCES: Nine electronic databases, cross-referencing, and expert review. STUDY SELECTION: Randomized controlled trials ≥4 weeks that included a D, E, DE and control (C) group in adults ≥18 years of age and in which data for one or more of the following were available: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG). DATA EXTRACTION: Dual data extraction by the first two authors. STATISTICAL ANALYSIS: Random-effects models as well as mixed-effects models for between-group differences. RESULTS: Seven-hundred and eighty-eight men and women from 6 studies were included. Non-overlapping 95% confidence intervals were observed for D and DE with respect to lowering TC, LDL-C and TG while reductions in E were limited to TG. No significant changes in HDL-C were observed. When compared to E, reductions in TC and LDL-C were greater for D and DE (p < 0.05 for all). CONCLUSIONS: Diet, especially DE, are superior to E for improving selected lipids and lipoproteins in adults.
Authors:
George A Kelley; Kristi S Kelley; Susan Roberts; William Haskell
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-9
Journal Detail:
Title:  Clinical nutrition (Edinburgh, Scotland)     Volume:  -     ISSN:  1532-1983     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309603     Medline TA:  Clin Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
Affiliation:
Department of Community Medicine, West Virginia University, Morgantown, WV, United States.
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