Document Detail


Comparison of adrenal vein sampling value between aldosterone producing adrenal adenoma and non-functioning adrenal adenoma: evaluation using receiver operating characteristic analysis.
MedLine Citation:
PMID:  16372697     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate adequate criteria for adrenal vein sampling values in patients with aldosterone producing adrenal adenoma (APA), retrospectively. MATERIAL AND METHODS: Between 1988 and 2002, 59 hypertensive patients (15 M and 44 F, aged 47.58 +/- 9.45 years) were referred to our hospital and diagnosed with APA based on established criteria. During the same period, 23 patients with non-functioning adrenal adenoma (11 M and 12 F aged 53.56 +/- 11.76 years) were diagnosed based on computed tomography and laboratory data. RESULTS: All 82 patients were enrolled in the present study. Bilateral adrenal vein sampling (AVS) for measurement of plasma aldosterone (A) and cortisol (C) was performed, and a receiver operating characteristics (ROC) analysis was conducted to establish the best criteria from the AVS-derived index in patients with APA. A (APA side)/A (contralateral side) was confirmed to provide the best diagnostic accuracy {(>2.5: right APA, sensitivity 83.3%, specificity 79.5%), (> 3: left APA, sensitivity 84.2%, specificity 76.9)}. The Az values for A (APA side)/A (contralateral side) were 0.8948 and 0.9260 for right and left APA, respectively. CONCLUSION: The A (APA side)/A (contralateral side) value was the best compromise for sensitivity and false-positive rate for lateralization of APA.
Authors:
Y Baba; H Hokotate; M Nakajo
Related Documents :
18716107 - Analysis of enhancement pattern of flat gallbladder wall thickening on mdct to differen...
24375817 - Carotid blowout in head and neck cancer patients - associated factors and treatment out...
23691737 - Radiation exposure and breast cancer: lessons from chernobyl.
24965107 - Radiation pathology: from thorotrast to the future beyond radioresistance.
24325407 - Trends of risk classification and primary therapy for japanese patients with prostate c...
19255307 - Second neoplasms in survivors of childhood cancer: findings from the childhood cancer s...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta radiologica (Stockholm, Sweden : 1987)     Volume:  46     ISSN:  0284-1851     ISO Abbreviation:  Acta Radiol     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-12-23     Completed Date:  2006-01-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8706123     Medline TA:  Acta Radiol     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  750-5     Citation Subset:  IM    
Affiliation:
Department of Radiology, Faculty of Medicine, Kagoshima University, Kagoshima, Japan. yasutaka@m3.kufm.kagoshima-u.ac.jp
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adenoma / diagnosis*
Adrenal Gland Neoplasms / diagnosis*
Adrenal Glands / blood supply*
Aldosterone / blood*
False Positive Reactions
Female
Functional Laterality
Humans
Hydrocortisone / blood*
Hyperaldosteronism / etiology*
Male
Middle Aged
ROC Curve*
Sensitivity and Specificity
Veins
Chemical
Reg. No./Substance:
50-23-7/Hydrocortisone; 52-39-1/Aldosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Ultrasound guidance in intracranial tumor resection: correlation with postoperative magnetic resonan...
Next Document:  Low-dose and standard-dose unenhanced helical computed tomography for the assessment of acute renal ...