Document Detail

Comparison of acute hemodynamic effects of lidocaine and procainamide for postoperative ventricular arrhythmias in dogs.
MedLine Citation:
PMID:  16822764     Owner:  NLM     Status:  MEDLINE    
Heart rate and systolic, diastolic, and mean pressures were measured in two groups of dogs during treatment of postoperative ventricular arrhythmias either with intravenous (IV) 2% lidocaine hydrochloride or procainamide hydrochloride. Hemodynamic parameters were not significantly changed after IV administration of either drug. Additionally, changes in hemodynamic parameters for dogs treated with 2% lidocaine were not significantly different from those of dogs treated with procainamide. When dosed appropriately in the clinical setting, one bolus of IV procainamide was safe for the treatment of postoperative ventricular arrhythmias.
John C Chandler; Eric Monnet; Andrew J Staatz
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of the American Animal Hospital Association     Volume:  42     ISSN:  1547-3317     ISO Abbreviation:  J Am Anim Hosp Assoc     Publication Date:    2006 Jul-Aug
Date Detail:
Created Date:  2006-07-06     Completed Date:  2007-08-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0415027     Medline TA:  J Am Anim Hosp Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  262-8     Citation Subset:  IM    
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, USA.
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MeSH Terms
Anti-Arrhythmia Agents / therapeutic use*
Arrhythmias, Cardiac / drug therapy,  veterinary*
Dog Diseases / drug therapy*
Heart Rate / drug effects
Lidocaine / therapeutic use*
Postoperative Complications / drug therapy,  veterinary
Procainamide / therapeutic use*
Treatment Outcome
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 137-58-6/Lidocaine; 51-06-9/Procainamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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