Document Detail

Comparison of the acute hemodynamic effect of right ventricular apex, outflow tract, and dual-site right ventricular pacing.
MedLine Citation:
PMID:  20946558     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We studied the acute effect of pacing at the right ventricular outflow tract (RVOT), right ventricular apex (RVA) and simultaneous RVA and RVOT-dual-site right ventricular pacing (DuRV) in random order on systolic function using impedance cardiography.
METHODS: Seventy-three patients (46 males), aged 52-89 years (mean 71.4 years) subjected to routine dual chamber pacemaker implantation with symptomatic chronic II or atrioventricular block, were included to the study.
RESULTS: DuRV pacing resulted in significantly higher cardiac index (CI) in comparison to RVOT and RVA and CI at RVOT was higher than at RVA pacing (2.46 vs 2.35 vs 2.28; P < 0.001). In patients with ejection fraction >50% significantly higher CI was observed during DuRV pacing when compared to RVOT and RVA pacing and there was no difference of CI between RVOT and RVA pacing (2.53 vs 2.41 vs 2.37; P < 0.001). In patients with ejection fraction <50%, DuRV and RVOT pacing resulted in significantly higher CI in comparison to RVA pacing while no difference in CI was observed between RVOT and DuRV pacing (2.28 vs 2.21 vs 2.09; P < 0.001).
CONCLUSION: Dual-site right ventricular pacing in comparison to RVA pacing improved cardiac systolic function. RVOT appeared to be more advantageous than RVA pacing in patients with impaired, but not in those with preserved left ventricular function. No clear hemodynamic benefit of DuRV in comparison to RVOT pacing in patients with impaired systolic function was observed.
Andrzej Rubaj; Piotr Rucinski; Tomasz Sodolski; Andrzej Bilan; Marcin Gulaj; Alicja Dabrowska-Kugacka; Andrzej Kutarski
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc     Volume:  15     ISSN:  1542-474X     ISO Abbreviation:  Ann Noninvasive Electrocardiol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-15     Completed Date:  2011-02-11     Revised Date:  2011-07-11    
Medline Journal Info:
Nlm Unique ID:  9607443     Medline TA:  Ann Noninvasive Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  353-9     Citation Subset:  IM    
Copyright Information:
©2010, Wiley Periodicals, Inc.
Department of Cardiology, Medical University of Lublin, Poland..
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MeSH Terms
Aged, 80 and over
Analysis of Variance
Atrioventricular Block / therapy*
Blood Pressure
Cardiac Pacing, Artificial / methods*
Cardiac Resynchronization Therapy Devices
Cardiography, Impedance / methods
Middle Aged
Pacemaker, Artificial*
Ventricular Dysfunction, Left
Ventricular Function, Right*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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