Document Detail

Comparison of Two Portable Lactate Meters in Dogs.
MedLine Citation:
PMID:  23148138     Owner:  NLM     Status:  Publisher    
The objective of this study was to compare two portable lactate analyzers for testing canine patients in a clinical setting with a previously accepted methodology for measuring plasma lactate. Between Jan 1, 2005 and Jun 1, 2006, all samples were analyzed using two different portable analyzers (devices A and B), and 86 of those samples were also analyzed by a reference laboratory (REF). The concordance correlation coefficient (CCC) for device A and the REF was 0.949 (95% confidence interval [95% CI], 0.923-0.966). For device B and REF, the CCC was 0.990 (95% CI, 0.985-0.993). Only 8 of 85 samples (9.4%) exceeded a relative difference of 20% for device B (note that 1 of the 86 samples was not included because the lactate level fell below the detectable limit of device B), but 48 of 85 samples (56.5%) exceeded a relative difference of 20% for device A. Both portable lactate analyzers appeared to be effective in detecting clinically significant elevations in plasma lactate compared with the REF but device B had better agreement. A positive correlation among all three analyzers existed; however, the analyzers do not yield directly interchangeable results.
Michael H Karagiannis; Fred A Mann; Richard W Madsen; Linda M Berent; Rebecca Greer
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-12
Journal Detail:
Title:  Journal of the American Animal Hospital Association     Volume:  -     ISSN:  1547-3317     ISO Abbreviation:  J Am Anim Hosp Assoc     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0415027     Medline TA:  J Am Anim Hosp Assoc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Veterinary Specialty Services, Manchester, MO, University of Missouri-Columbia Veterinary Medical Teaching Hospital, Columbia, MO; and University of Missouri Medical Research Office, University of Columbia, Columbia, MO (R.M.).
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