Document Detail

A comparison of the reliability of smartphone apps for opioid conversion.
MedLine Citation:
PMID:  23322549     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Many medical professionals use smartphone applications (apps) on a daily basis to support clinical decision making. Opioid switching (conversion of one opioid to another at equianalgesic dose) is common in clinical practice and often challenging for doctors. Apps providing an opioid conversion tool can therefore be a useful resource. Despite rapid growth in the use of medical apps, the lack of robust regulation and peer review to ensure the accuracy and reliability of app content is currently an area of concern.
METHOD: We searched major online app stores for apps providing an opioid dose conversion tool. We assessed output variability between apps in the dose calculation of seven opioid switches, as well as assessing the level of professional medical involvement in the authorship, creation and design of the apps.
RESULTS: Of 23 different apps identified, more than half (n = 12; 52 %) had no stated medical professional involvement and only 11 (48 %) apps provided direct references to primary sources for their opioid conversion ratios. Conversion of 1 mg of oral morphine to oral codeine demonstrated the largest conversion output range (median 6.67 mg, range 3.333-12 mg). Conversion of 1 mg of oral morphine to methadone ranged from 0.05-0.67 mg, with only 44 % of methadone-converting apps (n = 4) commenting that the conversion ratio changes with magnitude of methadone dose. Overall, 35 % of apps (n = 8) did not warn the user about the standard practice of dose reduction when opioid switching. There was a statistically significant difference in the mean conversion output for hydromorphone (oral) between apps with and without medical professional involvement (0.2256 vs 0.2536; p = 0.0377).
CONCLUSIONS: There are significant concerns with regard to the reliability of information provided by apps offering opioid dose conversion, with lack of information regarding evidence-based content and peer review in many cases. It is crucial that better regulation of medical apps is instigated in order to ensure that patient safety is maintained.
Faye Haffey; Richard R W Brady; Simon Maxwell
Related Documents :
19126569 - A pilot open label, single dose trial of fenobam in adults with fragile x syndrome.
11374699 - High-dose ursodeoxycholic acid as a therapy for patients with primary sclerosing cholan...
25133789 - Influence of metal of the applicator on the dose distribution during brachytherapy.
9126089 - Ejaculation-retarding properties of paroxetine in patients with primary premature ejacu...
20556789 - Sapropterin dihydrochloride for phenylketonuria.
14627859 - Percutaneous 17beta-estradiol gel for the treatment of vasomotor symptoms in postmenopa...
3706799 - Distribution in cerebrospinal fluid, blood, and lymph of epidurally injected morphine a...
319119 - Aerosolized terbutaline sulfate--an evalution of efficacy and side effects in patients ...
7947529 - Early abortion induction by a combination of mifepristone and oral misoprostol: a compa...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Drug safety     Volume:  36     ISSN:  0114-5916     ISO Abbreviation:  Drug Saf     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-02-11     Completed Date:  2013-07-02     Revised Date:  2014-11-17    
Medline Journal Info:
Nlm Unique ID:  9002928     Medline TA:  Drug Saf     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  111-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Analgesics, Opioid / administration & dosage*
Cellular Phone / utilization*
Computers, Handheld / utilization
Dose-Response Relationship, Drug
Drug Dosage Calculations*
Medical Informatics Applications
Reg. No./Substance:
0/Analgesics, Opioid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  19-VNTR loci used in genotyping Chinese clinical Mycobacterium tuberculosis complex strains and in a...
Next Document:  Comparison of nanotube-protein corona composition in cell culture media.