Document Detail

Comparison of QT/RR relation based on a 15-s averaged ECG and a single beat ECG during atrial fibrillation.
MedLine Citation:
PMID:  21178289     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The aim of this study was to compare QT/RR relation based on a 15-s averaged beat ECG with a single beat ECG during atrial fibrillation (AF) and to determine which was better to estimate the QT interval after sinus restoration.
METHODS AND RESULTS: QT and RR intervals were measured using an automatic QT analyzing system in 33 patients who had both AF and sinus rhythm on the same 24-h Holter ECG recording. In 14 patients, antiarrhythmic drugs (AAD) were administered. QT/RR relations were analyzed from ECG waves obtained by the summation of consecutive QRS-T complexes during each 15-s period (QT/RR-average) and a single beat QRS-T (QT/RR-single). During sinus rhythm, the slope of QT/RR-average did not differ from that of QT/RR-single in patients with and without AAD. On the other hand, during AF, the slope of QT/RR-average was significantly greater than that of QT/RR-single (without AAD: 0.12±0.06 vs. 0.06±0.03, P<0.001; with AAD: 0.15±0.05 vs. 0.08±0.04, P<0.001). During AF, the QT interval at an RR interval of 1.2-s (QT-1.2) determined from QT/RR-average was significantly greater than QT-1.2 from QT/RR-single in patients with and without AAD. QT-1.2 in QT/RR-single during AF was significantly smaller than that during sinus rhythm but QT-1.2 in QT/RR-average during AF was not.
CONCLUSIONS: The QT interval after sinus restoration could be estimated better using QT/RR-average than using QT/RR-single during AF.
Akira Fujiki; Masao Sakabe
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article     Date:  2010-12-17
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  75     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2011  
Date Detail:
Created Date:  2011-01-28     Completed Date:  2011-05-23     Revised Date:  2012-01-09    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  274-9     Citation Subset:  IM    
Division of Cardiology, Shizuoka Red Cross Hospital, Shizuoka, Japan.
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MeSH Terms
Aged, 80 and over
Anti-Arrhythmia Agents / pharmacology,  therapeutic use
Antihypertensive Agents / pharmacology,  therapeutic use
Atrial Fibrillation / complications,  drug therapy,  physiopathology*
Electrocardiography, Ambulatory / drug effects,  methods*
Hypertension / complications,  drug therapy
Linear Models
Middle Aged
Reproducibility of Results
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 0/Antihypertensive Agents

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