Document Detail


Comparison of Pulmonary Gas Exchange According to Intraoperative Ventilation Modes for Mitral Valve Repair Surgery via Thoracotomy with One-Lung Ventilation: A Randomized Controlled Trial.
MedLine Citation:
PMID:  24480179     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: Impaired pulmonary gas exchange after cardiac surgeries with cardiopulmonary bypass (CPB) often occurs, and the selection of mechanical ventilation mode, pressure-controlled ventilation (PCV) or volume-controlled ventilation (VCV), may be important for preventing hypoxia and improving oxygenation. The authors hypothesized that patients with PCV would show better oxygenation, compared with VCV, during one-lung ventilation (OLV) for mitral valve repair surgery (MVP) via thoracotomy.
DESIGN: Randomized controlled trial.
SETTING: University teaching hospital.
PARTICIPANTS: Sixty patients in each group.
INTERVENTIONS: MVP was performed using thoracotomy with OLV by PCV or VCV.
MEASUREMENTS AND MAIN RESULTS: Arterial partial pressure of oxygen (PaO2) and fraction of inspired oxygen (FIO2) were measured before anesthesia induction (T0), at skin incision (T1), after administration of heparin (T2), at 30 minutes after CPB weaning (T3), just before departure from the operating room to the intensive care unit (ICU) (T4), and 1 hour after ICU admission (T5), and PaO2/FIO2 ratio was calculated. Peak inspiratory pressure (PIP) and mean inspiratory pressure (Pmean) were recorded at T1, T2, T3, and T4. No significant difference was noted in the PaO2/FIO2 ratio between the groups at any measured point. PIP in the PCV group at all measured points was lower than that in the VCV group (T1, p<0.001; T2, p<0.001; T3, p<0.001; T4, p = 0.025, respectively). Pmean was not different between the two groups at any measured point.
CONCLUSIONS: PCV during OLV in patients undergoing MVP via a thoracotomy with OLV showed lower PIP compared with VCV, but this did not improve pulmonary gas exchange.
Authors:
Woon-Seok Kang; Seong-Hyop Kim; Jin Woo Chung
Related Documents :
16250719 - Prediction of resting cardiovascular functioning in youth with family histories of esse...
557279 - Cardiovascular control in the milan strain of spontaneously hypertensive rat (mhs) at "...
24149669 - Battery life of portable home ventilators: effects of the ventilatory settings.
23957599 - Adherence to oxygenation and ventilation targets in mechanically ventilated premature a...
2913109 - Left ventricular shape, afterload and survival in idiopathic dilated cardiomyopathy.
17150259 - Spatial exploration behaviour in an extended labyrinth in patients with panic disorder ...
20333889 - Where is end expiration? measuring pawp when the patient is on pressure support ventila...
2669649 - Right ventricular function and high-frequency positive-pressure ventilation during coro...
23726159 - Blood-pressure targets in patients with recent lacunar stroke: the sps3 randomised trial.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-1-27
Journal Detail:
Title:  Journal of cardiothoracic and vascular anesthesia     Volume:  -     ISSN:  1532-8422     ISO Abbreviation:  J. Cardiothorac. Vasc. Anesth.     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-1-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110208     Medline TA:  J Cardiothorac Vasc Anesth     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2014 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Expression of miR-15/107 Family MicroRNAs in Human Tissues and Cultured Rat Brain Cells.
Next Document:  The Asia-Pacific Evaluation of Cardiovascular Therapies (ASPECT) Collaboration -Improving the qualit...