| Comparison of the prognostic predictive value of the TIMI, PAMI, CADILLAC, and GRACE risk scores in STEACS undergoing primary or rescue PCI. | |
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MedLine Citation:
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PMID: 22281285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION AND OBJECTIVES: We sought to compare the predictive value of the Thrombolysis In Myocardial Infarction (TIMI), Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC), Primary Angioplasty in Myocardial Infarction (PAMI), and Global Registry for Acute Coronary Events (GRACE) scores for the outcome of ST-segment elevation acute coronary syndrome undergoing urgent percutaneous coronary intervention. METHODS: We performed a retrospective analysis of a cohort composed of all consecutive patients with ST-segment elevation acute coronary syndrome treated by urgent percutaneous coronary intervention between 2006 and 2010 (n=1503). TIMI, PAMI, CADILLAC, and GRACE risk scores were calculated for each patient according to different clinical variables. We assessed the predictive accuracy of these scores for death, reinfarction, and target-vessel revascularization at 30 days and 1 year, using the C statistic, which was obtained by means of logistic regression and ROC curves. RESULTS: The TIMI, PAMI, CADILLAC and GRACE showed an excellent predictive value for 30-day and 1-year mortality (C statistic range, 0.8-0.9), with superiority of the TIMI, CADILLAC, and GRACE risk models. The performance of these 4 scores was poor for both reinfarction and target-vessel revascularization (C statistic, 0.5-0.6). CONCLUSIONS: The TIMI, PAMI, CADILLAC, and GRACE scores provide excellent information to stratify the risk of mortality in patients treated by percutaneous coronary intervention. The TIMI, CADILLAC, and GRACE models have higher predictive accuracy. The usefulness of these models for reinfarction and target-vessel revascularization prediction is questionable. |
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Authors:
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Elizabet Méndez-Eirín; Xacobe Flores-Ríos; Fernando García-López; Alberto J Pérez-Pérez; Rodrigo Estévez-Loureiro; Pablo Piñón-Esteban; Guillermo Aldama-López; Jorge Salgado-Fernández; Ramón A Calviño-Santos; José M Vázquez Rodríguez; Nicolás Vázquez-González; Alfonso Castro-Beiras |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2012-01-26 |
Journal Detail:
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Title: Revista española de cardiología (English ed.) Volume: 65 ISSN: 1885-5857 ISO Abbreviation: Rev Esp Cardiol (Engl Ed) Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-02-22 Completed Date: 2012-07-02 Revised Date: 2013-05-24 |
Medline Journal Info:
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Nlm Unique ID: 101587954 Medline TA: Rev Esp Cardiol (Engl Ed) Country: Spain |
Other Details:
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Languages: eng; spa Pagination: 227-33 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Sociedad Española de Cardiología. Published by Elsevier Espana. All rights reserved. |
Affiliation:
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Unidad de Hemodinámica, Servicio de Cardiología, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Coronary Syndrome
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surgery Aged Angioplasty, Balloon, Coronary* Antibodies, Monoclonal / therapeutic use* Cohort Studies Coronary Disease / complications, mortality, surgery* Female Humans Immunoglobulin Fab Fragments / therapeutic use* Logistic Models Male Middle Aged Myocardial Infarction / drug therapy*, surgery* Myocardial Revascularization Platelet Aggregation Inhibitors / therapeutic use* Postoperative Complications / drug therapy*, mortality Predictive Value of Tests Prognosis ROC Curve Recurrence Registries Retrospective Studies Risk Assessment Thrombolytic Therapy* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Immunoglobulin Fab Fragments; 0/Platelet Aggregation Inhibitors; X85G7936GV/abciximab |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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