Document Detail

Comparison of measures of adiposity in identifying cardiovascular disease risk among Ethiopian adults.
MedLine Citation:
PMID:  21546936     Owner:  NLM     Status:  MEDLINE    
We sought to determine which measures of adiposity can predict cardiovascular disease (CVD) risk and to evaluate the extent to which overall and abdominal adiposity are associated with cardiometabolic risk factors among working adults in Ethiopia. This was a cross-sectional study of 1,853 individuals (1,125 men, 728 women) in Addis Ababa, Ethiopia. The World Health Organization STEPwise approach was used to collect sociodemographic data, anthropometric measurements, and blood samples among study subjects. Fasting blood glucose (FBG) and lipid concentrations were measured using standard approaches. Spearman's rank correlation, receiver operating characteristic (ROC) curves, and logistic regression were employed to determine the association and predictive ability (with respect to CVD risk factors) of four measures of adiposity: BMI, waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR). Overall, FBG is best associated with WHtR in men and WC in women. Systolic blood pressure (SBP) is most strongly associated with BMI in men, but with WC in women. Compared to those with low BMI and low WC, the risk of having CVD is the highest for those with high BMI and high WC and those with high WC and low BMI. Review of ROC curves indicated that WC is the best predictor of CVD risk among study subjects. Findings from our study underscore the feasibility and face validity of using simple measures of central and overall adiposity in identifying CVD risk in resource-poor settings.
Wint S Wai; Ranjodh S Dhami; Bizu Gelaye; Belaineh Girma; Seblewengel Lemma; Yemane Berhane; Tamrat Bekele; Atsede Khali; Michelle A Williams
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural     Date:  2011-05-05
Journal Detail:
Title:  Obesity (Silver Spring, Md.)     Volume:  20     ISSN:  1930-739X     ISO Abbreviation:  Obesity (Silver Spring)     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-28     Completed Date:  2013-01-02     Revised Date:  2014-09-24    
Medline Journal Info:
Nlm Unique ID:  101264860     Medline TA:  Obesity (Silver Spring)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1887-95     Citation Subset:  IM    
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MeSH Terms
Alcohol Drinking / epidemiology
Blood Glucose / metabolism
Blood Pressure
Body Mass Index*
Cardiovascular Diseases / blood,  epidemiology*,  physiopathology
Cross-Sectional Studies
Ethiopia / epidemiology
Fasting / blood
Hypertension / epidemiology
Middle Aged
Predictive Value of Tests
ROC Curve
Risk Assessment
Risk Factors
Sedentary Lifestyle
Sex Factors
Smoking / epidemiology
Waist Circumference*
Waist-Hip Ratio*
Young Adult
Grant Support
T37 MD001449/MD/NIMHD NIH HHS; T37 MD001449-14/MD/NIMHD NIH HHS; T37 MD001449-15/MD/NIMHD NIH HHS; T37-MD001449/MD/NIMHD NIH HHS
Reg. No./Substance:
0/Blood Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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