| A Comparison of Mean Displacement Values Using High b-Value Q-Space Diffusion-weighted MRI with Conventional Apparent Diffusion Coefficients in Patients with Stroke. | |
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MedLine Citation:
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PMID: 21419670 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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RATIONALE AND OBJECTIVES: Q-space analysis using high b-value diffusion-weighted magnetic resonance (MR) data provides information on tissue microstructure in contrast to conventional MR imaging (MRI) based on low b-value diffusion-weighted imaging (DWI). The purpose of this study was to evaluate the use of mean displacement (MDP) map in stroke patients using q-space diffusion-weighted MRI (QSI). MATERIALS AND METHODS: Twenty-one patients presenting with a total of 22 acute or subacute cerebral infarctions were included. MR protocol consisted of conventional MR sequences, DWI (b-value; 1000 s/mm(2)) and QSI (b-value; maximum 12,000 s/mm(2)). Apparent diffusion coefficient (ADC) maps of conventional DWI and MDP maps of QSI data were obtained and compared in the ischemic lesions and corresponding normal tissues. RESULTS: Decreased ADC values were present in all lesions. There was no correlation between ADC and MDP values in the lesions (r = 0.21). MDP values of the lesions were 8.60 ± 1.26 μm (mean ± SD). Most of the lesions (16/22) had higher MDP values than normal brain tissue. Three lesions showed lower MDP values and three showed mixed MDP values. CONCLUSIONS: The MDP maps using QSI data provides additional information for stroke patients compared to conventional DWI. |
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Authors:
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Masaaki Hori; Utaroh Motosugi; Zareen Fatima; Hiroshi Kumagai; Satoshi Ikenaga; Keiichi Ishigame; Shigeki Aoki; Toshiyuki Onodera; Kazuo Yagi; Tsutomu Araki |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-17 |
Journal Detail:
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Title: Academic radiology Volume: - ISSN: 1878-4046 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9440159 Medline TA: Acad Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 AUR. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Radiology, University of Yamanashi, Yamanashi, Japan; Department of Radiology, School of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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