Document Detail

Comparison of Maxon suture with Vicryl, chromic catgut, and PDS sutures in fascial closure in rats.
MedLine Citation:
PMID:  3126470     Owner:  NLM     Status:  MEDLINE    
Two hundred ten rats were randomized into one of five study groups to compare standard absorbable sutures with a new synthetic absorbable suture. We evaluated Maxon (polyglyconate), Vicryl (polyglactin), chromic catgut (catgut), and PDS (polydioxanone) with respect to tissue inflammatory reaction, knot security, suture tensile strength, and suture absorption. The results indicate that Maxon and PDS elicited a lower degree of chronic inflammation when compared with Vicryl and chromic catgut. The tensile strengths of Maxon and Vicryl significantly exceeded those of PDS and chromic catgut during the critical period of wound healing. Maxon and PDS retained a larger percentage of tensile strength during the long postoperative period, whereas Vicryl and chromic catgut were mostly absorbed. Maxon is an excellent addition to the armamentarium of the gynecologic surgeon.
L E Sanz; J A Patterson; R Kamath; G Willett; S W Ahmed; A B Butterfield
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  71     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-04-15     Completed Date:  1988-04-15     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  418-22     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Georgetown University School of Medicine, Washington, DC.
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MeSH Terms
Catgut / adverse effects
Inflammation / chemically induced
Materials Testing*
Polyesters / adverse effects
Polyglactin 910 / adverse effects
Polymers / adverse effects
Rats, Inbred Strains
Tensile Strength
Reg. No./Substance:
0/Polyesters; 0/Polymers; 31621-87-1/Polydioxanone; 34346-01-5/Polyglactin 910; 75734-93-9/polyglyconate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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