Document Detail


Comparison of local anesthetic effects of tramadol with prilocaine during circumcision procedure.
MedLine Citation:
PMID:  19854483     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To compare the local anesthetic effects of tramadol hydrochloride with prilocaine for circumcision procedure. METHODS: This study included 40 patients with American Surgical Association-I scores. Patients were randomly allocated to receive either 5% tramadol (2 mg/kg) plus adrenaline (0.0125/mL) (group 1, n = 20) or 2% prilocaine plus adrenaline (0.0125/mL) (group 2, n = 20). The degree of burning sensation and pain at the injection site were documented. Sensory block was assessed 1 minute after injection and the patients were asked to grade touch and pinprick sensation. Five minutes after drug administration, incision was performed and intensity of pain, felt by the patient was evaluated on a 4-point scale (0-3). Pain at the injection site and local skin reactions were also recorded. RESULTS: Mean ages were 9.7 and 10.3 years for groups 1 and 2, respectively. Mean duration of surgery was 19.6 minutes. In control visit, 2 of 20 (10%) in group 1 and 10 of 20 (50%) children in group 2 reported extra need for oral ibuprofen (P <.05). First analgesic medication time was 9.5 (+/- 2.1) hours in group 1 and 8.7 (+/- 3.1) hours in group 2 (P >.05). Total postoperative ibuprofen consumptions were 10 and 50 mg for groups 1 and 2, respectively (P <.05). CONCLUSIONS: A combination of tramadol 5% plus adrenaline can provide a safe and effective local anesthesia during circumcision procedure and postoperative period in children.
Authors:
Eksal Kargi; Ahmet I?ikdemir; H?sn? Tokg?z; B?lent Erol; Fulden I?ikdemir; Volkan Hanci; Cem Payasli
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2009-10-24
Journal Detail:
Title:  Urology     Volume:  75     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-09     Completed Date:  2010-04-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  672-5     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Plastic and Reconstructive Surgery, Karaelmas University School of Medicine, Zonguldak, Turkey. eksalk@superonline.com
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MeSH Terms
Descriptor/Qualifier:
Analgesics, Opioid / therapeutic use*
Anesthesia, Local*
Anesthetics, Local / therapeutic use*
Child
Circumcision, Male / adverse effects*
Double-Blind Method
Drug Therapy, Combination
Humans
Male
Pain / etiology*,  prevention & control*
Pain, Postoperative / prevention & control
Prilocaine / therapeutic use*
Tramadol / therapeutic use*
Chemical
Reg. No./Substance:
0/Analgesics, Opioid; 0/Anesthetics, Local; 27203-92-5/Tramadol; 721-50-6/Prilocaine
Comments/Corrections
Comment In:
Urology. 2010 Mar;75(3):675; author reply 675   [PMID:  20211377 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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