Document Detail

Comparison of Indium-111 platelet scintigraphy and two-dimensional echocardiography in the diagnosis of left ventricular thrombi.
MedLine Citation:
PMID:  7078607     Owner:  NLM     Status:  MEDLINE    
In a study comparing indium-111 platelet scintigraphy and two-dimensional echocardiography as methods of identifying left ventricular thrombi, the results obtained with both techniques were verified at surgery or autopsy in 53 patients--34 with left ventricular aneurysms, and 19 with mitral-valve disease. Left ventricular thrombi were found at surgery or autopsy in 14 of the patients with aneurysms and in none of those with mitral-valve disease. Thirteen of 53 echocardiograms (25 per cent) were technically inadequate and excluded from the analysis. In the group with aneurysms, the sensitivity of scintigraphy in detecting thrombi was 71 per cent, and that of echocardiography was 77 per cent. The specificity of scintigraphy was 100 per cent, and that of echocardiography was 93 per cent. We conclude that indium-111 platelet scintigraphy and two-dimensional echocardiography have useful and complementary roles in the detection of left ventricular thrombi. Both these noninvasive techniques can be used to monitor therapy.
M D Ezekowitz; D A Wilson; E O Smith; R D Burow; L H Harrison; D E Parker; R C Elkins; M Peyton; F B Taylor
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The New England journal of medicine     Volume:  306     ISSN:  0028-4793     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  1982 Jun 
Date Detail:
Created Date:  1982-07-22     Completed Date:  1982-07-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1509-13     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Platelets / radionuclide imaging*
Heart Diseases / diagnosis*,  radionuclide imaging,  surgery
Heart Ventricles
Indium / diagnostic use
Middle Aged
Radioisotopes / diagnostic use
Thrombosis / diagnosis*,  radionuclide imaging,  surgery
Grant Support
Reg. No./Substance:
0/Radioisotopes; 7440-74-6/Indium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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