| Comparison of Impella and intra-aortic balloon pump in high-risk percutaneous coronary intervention: Vascular complications and incidence of bleeding. | |
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MedLine Citation:
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PMID: 23215746 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective: Compare vascular complications and incidence of bleeding of Impella 2.5 and intra-aortic balloon pump (IABP) in high-risk percutaneous coronary interventions (PCI). Background: Large arterial sheath size for device insertion is associated with vascular and/or bleeding complications; gastrointestinal bleeding may also occur with anti-coagulation use. Methods: Patients with an acute coronary syndrome receiving Impella 2.5 or IABP during high-risk PCI were studied (13 Impella; 62 IABP). Vascular complications and incidence of bleeding were compared. Results: Post-procedure hematocrit was similar between groups. Blood transfusion occurred in 38.4% and 32.2% of patients in the Impella and IABP groups, respectively (P = NS); 65.3%, 30.7% and 3.8% of bleeding were due to vascular access site/procedure related, gastrointestinal and genitourinary, respectively. There was no statistical significant difference in vascular complications between the Impella and IABP groups (15.3% and 6.4% of patients, respectively); mesenteric ischemia (n = 1) and aortic rupture (n = 1) were only in the IABP group. In-hospital and one-year mortality were not statistically significant between groups. Conclusion: Impella can be used as safely as IABP during high-risk PCI with similar vascular and bleeding complications. Importantly, approximately one third of bleeding was from the gastrointestinal system warranting careful prophylactic measures and monitoring. |
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Authors:
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Konstantinos Dean Boudoulas; Andrew Pederzolli; Uksha Saini; Richard J Gumina; Ernest L Mazzaferri; Michael Davis; Charles A Bush; Quinn Capers; Raymond Magorien; Vincent J Pompili |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acute cardiac care Volume: 14 ISSN: 1748-295X ISO Abbreviation: Acute Card Care Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101276603 Medline TA: Acute Card Care Country: England |
Other Details:
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Languages: eng Pagination: 120-4 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular Medicine, Section of Interventional Cardiology, The Ohio State University , Columbus, Ohio , USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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