| Comparison of IgG antibody profiles by immunoblotting in patients with acute and previous Toxoplasma gondii infection. | |
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MedLine Citation:
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PMID: 1856289 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The IgG antibody profile to Toxoplasma gondii proteins of less than 37 kilodaltons in sera from patients with acute and previous infection was studied by immunoblotting. Bands at 28, 29, and 36 kilodaltons were more common in acute infection (10 out of 10, nine out of 10, and nine out of 10, respectively) compared with previous infection (five out of 10, four out of 10, and one out of 10, respectively). The 6 kilodalton band was present in 10 out of 10 sera from patients with acute infection and five out of 10 sera from those with previous infection. A new observation is a doublet of bands of 22-25 kilodaltons present only in sera from patients with acute infection. This doublet may be a more reliable indicator of acute infection than the 6 kilodalton band. |
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Authors:
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I L Moir; M M Davidson; D O Ho-Yen |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of clinical pathology Volume: 44 ISSN: 0021-9746 ISO Abbreviation: J. Clin. Pathol. Publication Date: 1991 Jul |
Date Detail:
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Created Date: 1991-08-27 Completed Date: 1991-08-27 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0376601 Medline TA: J Clin Pathol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 569-72 Citation Subset: AIM; IM |
Affiliation:
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Department of Microbiology, Raigmore Hospital, Inverness. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Animals Antibodies, Protozoan / analysis* Humans Immunoblotting / methods Immunoglobulin G / analysis* Protozoan Proteins / immunology Toxoplasma / immunology* Toxoplasmosis / diagnosis, immunology* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Protozoan; 0/Immunoglobulin G; 0/Protozoan Proteins |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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