Document Detail


Comparison of IgG antibody profiles by immunoblotting in patients with acute and previous Toxoplasma gondii infection.
MedLine Citation:
PMID:  1856289     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The IgG antibody profile to Toxoplasma gondii proteins of less than 37 kilodaltons in sera from patients with acute and previous infection was studied by immunoblotting. Bands at 28, 29, and 36 kilodaltons were more common in acute infection (10 out of 10, nine out of 10, and nine out of 10, respectively) compared with previous infection (five out of 10, four out of 10, and one out of 10, respectively). The 6 kilodalton band was present in 10 out of 10 sera from patients with acute infection and five out of 10 sera from those with previous infection. A new observation is a doublet of bands of 22-25 kilodaltons present only in sera from patients with acute infection. This doublet may be a more reliable indicator of acute infection than the 6 kilodalton band.
Authors:
I L Moir; M M Davidson; D O Ho-Yen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  44     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1991 Jul 
Date Detail:
Created Date:  1991-08-27     Completed Date:  1991-08-27     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  569-72     Citation Subset:  AIM; IM    
Affiliation:
Department of Microbiology, Raigmore Hospital, Inverness.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Animals
Antibodies, Protozoan / analysis*
Humans
Immunoblotting / methods
Immunoglobulin G / analysis*
Protozoan Proteins / immunology
Toxoplasma / immunology*
Toxoplasmosis / diagnosis,  immunology*
Chemical
Reg. No./Substance:
0/Antibodies, Protozoan; 0/Immunoglobulin G; 0/Protozoan Proteins
Comments/Corrections

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