Document Detail

Comparison of frontomaxillary facial angles using both 2D and 3D ultrasound at 11+0 to 13+6 weeks of gestation.
MedLine Citation:
PMID:  20587987     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: The aim of this study is to (i) directly compare both two-dimensional (2D) and three-dimensional (3D) frontomaxillary facial angle (FMFA) in first trimester, and (ii) to assess the ease with which both may be performed.
MATERIALS AND METHODS: Both 3D volumes of the fetal head and 2D fetal profiles were collected from 251 consenting patients during routine first-trimester nuchal translucency (NT) screening. The FMFA in 2D was measured at the time of the NT screening. The 3D FMFA was measured offline.
RESULTS: The 2D FMFA was systematically higher than the 3D FMFA. The difference in 3D-2D FMFA was statistically significant from 11+0 to 12+3 weeks. From 12+4 to 13+6 weeks the difference was no longer significant with p = 0.06. Performing the measurement did not unduly increase the time of the study. Even for the experienced sonographer the technique is technically difficult, relying on many factors for accurate caliper placement.
DISCUSSION: The 2D FMFA is greater than the 3D angle. This was found in previous studies, but not thought to be statistically significant. The difference decreased with increasing gestational age. There is a learning curve associated with performing this measurement. Normative data for both 2D and 3D, incorporating ethnicity, may be necessary before inclusion in the first-trimester algorithm.
Jennifer Alphonse; Jennifer Cox; Jill Clarke; Philip J Schluter; Andrew McLennan
Related Documents :
12666217 - The role of fetal nuchal translucency and ductus venosus doppler at 11-14 weeks of gest...
11251917 - Relationship between fetal nuchal translucency and crown-rump length in an asian popula...
18441727 - Abnormal folate metabolism as a risk factor for first-trimester spontaneous abortion.
17152117 - Free fetal dna in maternal circulation: a potential prognostic marker for chromosomal a...
9022527 - Body fat estimation in late pregnancy and early postpartum: comparison of two-, three-,...
6846237 - Fetal iron balance in the rat.
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2010-06-30
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  28     ISSN:  1421-9964     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:  2010  
Date Detail:
Created Date:  2010-08-09     Completed Date:  2010-12-03     Revised Date:  2011-03-22    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  14-21     Citation Subset:  IM    
Copyright Information:
Copyright 2010 S. Karger AG, Basel.
Sydney Ultrasound for Women, Bella Vista, NSW, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Age Factors
Down Syndrome / ultrasonography*
Face / embryology,  ultrasonography*
Fetal Development
Gestational Age
Head / embryology,  ultrasonography
Imaging, Three-Dimensional*
Pregnancy Trimester, First
Prospective Studies
Sensitivity and Specificity
Ultrasonography, Prenatal*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Limb salvage--at which costs, which risks?
Next Document:  Contribution of magnetic resonance imaging to prenatal differential diagnosis of renal tumors: repor...