| A comparison of endothelial cell loss after phacoemulsification in penetrating keratoplasty patients and normal patients. | |
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MedLine Citation:
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PMID: 20308877 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To compare phacoemulsification-related endothelial cell loss in transplanted corneas and normal corneas. METHODS: Forty-nine patients who underwent phacoemulsification/intraocular lens insertion after penetrating keratoplasty (PK-CAT group) (50 eyes) were compared with 65 patients who underwent phacoemulsification/intraocular lens insertion only (CAT group) (100 eyes). The PK-CAT group was divided into corneal endothelial dysfunction (CED) and opacity subgroups according to recipient endothelial function. Effective phacoemulsification time and endothelial density were analyzed. RESULTS: The endothelial cell density after cataract surgery from 1 month (1772.72 +/- 315.89) to 24 months (917.25 +/- 372.75) in the PK-CAT group was significantly lower than that before cataract surgery (2189.36 +/- 358.68) (P < 0.05) but that in CAT group was not significantly different from baseline during follow-up time (P < 0.05). The rate of graft survival in the opacity subgroup (82.0%) of the PK-CAT group was higher than that in the CED subgroup (54.5%) after 2 years (P < 0.05). The mean endothelial density in the opacity subgroup (1216.73 +/- 271.63 cells/mm2) of the PK-CAT group was significantly higher than that in the CED subgroup (632.50 +/- 238.29 cells/mm2) at 2 years after cataract surgery (P < 0.05). CONCLUSIONS: The phacoemulsification-related endothelial cell loss in transplanted corneas was higher than that in normal corneas. A possible factor contributing to higher endothelial cell loss in transplanted corneas is recipient endothelial dysfunction. |
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Authors:
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Eun Chul Kim; Man Soo Kim |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Cornea Volume: 29 ISSN: 1536-4798 ISO Abbreviation: Cornea Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-26 Completed Date: 2010-06-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8216186 Medline TA: Cornea Country: United States |
Other Details:
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Languages: eng Pagination: 510-5 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology and Visual Science, College of Medicine, Catholic University of Korea, Seoul, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Case-Control Studies Cell Count Corneal Endothelial Cell Loss / diagnosis, etiology* Endothelium, Corneal / pathology Female Follow-Up Studies Graft Survival Humans Keratoplasty, Penetrating* Lens Implantation, Intraocular Male Middle Aged Phacoemulsification / adverse effects* Retrospective Studies Risk Factors Visual Acuity / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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