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Comparison of Efficacy between Continuous Hemodiafiltration with a PMMA High-Performance Membrane Dialyzer and a PAN Membrane Hemofilter in the Treatment of Septic Shock Patients with Acute Renal Failure.
MedLine Citation:
PMID:  21865791     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The aim of this study was to investigate whether continuous hemodiafiltration (CHDF) with a high-performance membrane dialyzer made of polymethylmethacrylate (PMMA-CHDF) in the treatment of septic shock patients with acute renal failure (ARF) is clinically relevant. 30 patients were treated with PMMA-CHDF. 13 patients treated with CHDF used a hemofilter made of polyacrylonitrile membrane (PAN-CHDF). Systolic blood pressure significantly increased in the PMMA-CHDF group following 24 h of treatment (p < 0.01), whereas it did not improve in the PAN-CHDF group. Urine volume significantly increased in the PMMA-CHDF group following 24 h of treatment which was more than in the PAN-CHDF group (p < 0.05). 28-day survival was 83.3% in the PMMA-CHDF group and 30.8% in the PAN-CHDF group, respectively (p < 0.01). We can assume that PMMA-CHDF in the treatment of septic shock patients with ARF is clinically relevant.
Authors:
Kenichi Matsuda; Takeshi Moriguchi; Norikazu Harii; Masahiko Yanagisawa; Daiki Harada; Hisanori Sugawara
Publication Detail:
Type:  Journal Article     Date:  2011-08-08
Journal Detail:
Title:  Contributions to nephrology     Volume:  173     ISSN:  1662-2782     ISO Abbreviation:  Contrib Nephrol     Publication Date:  2011  
Date Detail:
Created Date:  2011-08-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7513582     Medline TA:  Contrib Nephrol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  182-90     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
Affiliation:
Department of Emergency and Critical Care Medicine, University of Yamanashi School of Medicine, Yamanashi, Japan.
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