Document Detail


Comparison of the Efficacy and Safety of Irbesartan and Olmesartan in Patients with Hypertension (EARTH Study).
MedLine Citation:
PMID:  22568596     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Fifty-four patients were randomly divided into irbesartan and olmesartan groups. Blood pressure (BP) was significantly decreased in all patients at 12 weeks. In particular, BP in patients who initially received irbesartan showed significant reductions. The equality of variance of BP in the irbesartan group was significantly smaller than that in the olmesartan group at 12 weeks. Blood concentrations of adiponectin were significantly increased in the irbesartan group at 12 weeks. Log [pentraxin-3] in the irbesartan group were significantly decreased. In conclusion, the ability of irbesartan to reduce BP is comparable to that of olmesartan with equivalent safety. Shin-ichiro Miura received lecture fees from Dainippon Sumitomo Pharma and Daiichi-Sankyo Co.
Authors:
Joji Morii; Shin-Ichiro Miura; Yuhei Shiga; Makoto Sugihara; Tadaaki Arimura; Hideto Sako; Bo Zhang; Yoshinari Uehara; Keijiro Saku
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-8
Journal Detail:
Title:  Clinical and experimental hypertension (New York, N.Y. : 1993)     Volume:  -     ISSN:  1525-6006     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9305929     Medline TA:  Clin Exp Hypertens     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Cardiology, Fukuoka University School of Medicine o, Fukuoka , Japan.
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