| Comparison of Diskus inhaler, a new multidose powder inhaler, with Diskhaler inhaler for the delivery of salmeterol to asthmatic patients. Canadian Study Group. | |
| | |
MedLine Citation:
|
PMID: 7592246 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Administration of the long-acting beta 2-adrenoceptor agonist salmeterol from a new, easy-to-operate, multidose powder inhaler (Diskus) containing 60 sealed doses in a foil strip has been compared with administration from a Diskhaler inhaler in a multicenter, double-blind, double-dummy, parallel-group study. Asthmatic patients taking anti-inflammatory treatment, with baseline FEV1 > or = 60% and < or = 90% predicted were treated for 4 weeks with salmeterol 50 micrograms twice daily from either the Diskus or Diskhaler inhaler. The two treatments were equivalent (90% CLs for the difference in mean morning PEFR: -2.2, 8.7 L/min). The Diskus inhaler was rated easier to use and was preferred by more patients than the Diskhaler inhaler (73% vs. 15%). |
| | |
Authors:
|
L P Boulet; R Cowie; P Johnston; D Krakovsky; S Mark |
Related Documents
:
|
20175346 - Ultrasound-guided intrauterine methotrexate injection of a failed gestation occurring p... 10843466 - Successful conservative treatment of endometrial carcinoma permitting subsequent pregna... 20226416 - Molar ectopic pregnancy in the uterine cornus. 1293896 - Conservative treatment of ectopic pregnancy with intramuscular administration of methot... 20499076 - Ivf conversion to iui in poor responders: an observational study. 18534816 - Epstein-barr virus infection in pregnancy--a prospective controlled study. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial |
Journal Detail:
|
Title: The Journal of asthma : official journal of the Association for the Care of Asthma Volume: 32 ISSN: 0277-0903 ISO Abbreviation: J Asthma Publication Date: 1995 |
Date Detail:
|
Created Date: 1995-12-22 Completed Date: 1995-12-22 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8106454 Medline TA: J Asthma Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 429-36 Citation Subset: IM |
Affiliation:
|
Hôpital Laval, Sainte-Foy, Quebec, Canada. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adrenergic beta-Agonists / administration & dosage*, therapeutic use Adult Aged Albuterol / administration & dosage, analogs & derivatives*, therapeutic use Asthma / drug therapy*, physiopathology Child Double-Blind Method Equipment Design Female Humans Male Middle Aged Nebulizers and Vaporizers* Patient Satisfaction Peak Expiratory Flow Rate Powders |
| Chemical | |
Reg. No./Substance:
|
0/Adrenergic beta-Agonists; 0/Powders; 18559-94-9/Albuterol; 89365-50-4/salmeterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Role of the adhesion molecule ICAM-1 in asthma.
Next Document: A preliminary study of factors that influence children's sense of competence to manage their asthma.