| Comparison of daily prostate positions during conformal radiation therapy of prostate cancer using an integrated CT-linear accelerator system: in-room CT image versus digitally reconstructed radiograph. | |
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MedLine Citation:
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PMID: 21436612 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purpose of this study is to quantify the magnitudes of the position shifts of internal structures together with the correlation between the day-to-day positioning of the prostate and the bony anatomy using an integrated CT-linear accelerator system for external beam radiation therapy for prostate cancer. MATERIALS AND METHODS: A total of 1176 pretreatment in-room CT images and their digitally reconstructed radio-graph (DRR) pairs from 33 patients were acquired over the course of the study. The differences between the isocenter of the prostate on in-room CT and the isocenter of the bony anatomy on DRR were analyzed. The agreement between positions in each direction was compared using Bland-Altman limits of agreement. RESULTS: The 95% limits of agreement in lateral (LR), superoinferior (SI), and anteroposterior (AP) directions were -2.98 to 2.49 mm, -4.69 to 5.75 mm, and -8.23 to 7.30 mm, respectively. The isocenter was localized to within 3.0 mm on in-room CT images and DRR 99.0% in LR, 85.1% in SI, and 85.9% in AP. CONCLUSIONS: Considerable differences between in-room CT images and DRR exist. These data demonstrate that there is a significantly greater shift in the SI and AP directions than in the lateral direction for the entire patient group. Applications such as our image guide system will, with routine clinical use, continue to improve the precision of external beam radiation therapy for prostate cancer. |
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Authors:
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Hideki Aoyama; Yoshiharu Azuma; Keiji Inamura |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of radiation research Volume: 52 ISSN: 1349-9157 ISO Abbreviation: J. Radiat. Res. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-03-25 Completed Date: 2011-07-05 Revised Date: 2012-03-28 |
Medline Journal Info:
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Nlm Unique ID: 0376611 Medline TA: J Radiat Res Country: Japan |
Other Details:
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Languages: eng Pagination: 220-8 Citation Subset: IM |
Affiliation:
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Central Division of Radiology, Okayama University Hospital, Okayama, Japan. h_aoyama@mail.bbexcite.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Bone and Bones / pathology Equipment Design Humans Image Processing, Computer-Assisted Male Middle Aged Particle Accelerators Patient Positioning* Prostate / pathology, radiation effects* Prostatic Neoplasms / diagnosis*, radiotherapy* Radiotherapy Planning, Computer-Assisted / methods Radiotherapy, Conformal / methods* Reproducibility of Results Tomography, X-Ray Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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