Document Detail

Comparison of Crinone 8% intravaginal gel and intramuscular progesterone supplementation for in vitro fertilization/embryo transfer in women under age 40: interim analysis of a prospective randomized trial.
MedLine Citation:
PMID:  17572412     Owner:  NLM     Status:  MEDLINE    
This study was performed to compare the efficacy of Crinone 8% intravaginal gel and intramuscular progesterone (IMP) supplementation for luteal phase support in women under age 40 undergoing IVF-ET. Results of the interim analysis of this rigorously designed prospective randomized controlled study are presented. Pregnancy rates, implantation rates, and early spontaneous abortion rates were similar for patients receiving Crinone or IMP, whereas fewer side effects and greater overall satisfaction were reported by women receiving Crinone.
Elena Yanushpolsky; Shelley Hurwitz; Louise Greenberg; Catherine Racowsky; Mark D Hornstein
Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2007-06-18
Journal Detail:
Title:  Fertility and sterility     Volume:  89     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-15     Completed Date:  2008-03-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  485-7     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
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MeSH Terms
Age Factors
Embryo Implantation / drug effects
Embryo Transfer*
Fertilization in Vitro / methods*
Injections, Intramuscular
Maternal Age
Pregnancy Rate
Progesterone / administration & dosage*,  analogs & derivatives*
Statistics as Topic / methods
Treatment Outcome
Vaginal Creams, Foams, and Jellies / chemistry
Reg. No./Substance:
0/Crinone; 0/Vaginal Creams, Foams, and Jellies; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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