| Comparison of classification systems for congenital melanocytic nevi. | |
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MedLine Citation:
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PMID: 20584038 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Congenital melanocytic nevi (CMNs) are found in approximately 1% of newborn infants, but these represent only a small proportion of the total population of nevi. They vary widely in size, from a small spot to a large area. Later in childhood, these lesions become thickened, verrucous, and hairy. Giant CMNs predispose to malignant melanoma, with a reported incidence of 2% to 31%. OBJECTIVE: To compare three different classification methods of the CMNs to determine which is most accurate. PARTICIPANTS AND METHODS: Sixty patients were included in the study (34 male, 26 female), with an average age of 17.4 (range 3-32). The nevi were evaluated using three different classification methods: total area of the nevus (in cm(2)), greatest nevus dimension, and percentage of nevus surface area to total patient body surface area. An appropriate treatment procedure for each case was applied, and participants were followed from 1997 to 2007. RESULTS: Malignant transformation was noted in 15.4% of participants with congenital nevi, which was confirmed histopathologically after excision. CONCLUSION: We recommend the calculation of total nevus area as the most useful method for assessment of the risk of developing melanoma in a CMN. The authors have indicated no significant interest with commercial supporters. |
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Authors:
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Arif Turkmen; Daghan Isik; Mehmet Bekerecioglu |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Volume: 36 ISSN: 1524-4725 ISO Abbreviation: Dermatol Surg Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-29 Completed Date: 2010-12-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9504371 Medline TA: Dermatol Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1554-62 Citation Subset: IM |
Copyright Information:
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© 2010 by the American Society for Dermatologic Surgery, Inc. |
Affiliation:
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Department of Plastic, Reconstructive, and Aesthetic Surgery, Gaziantep University Medical Faculty, Gaziantep, Turkey. turkmenarif@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Cell Transformation, Neoplastic Child Child, Preschool Female Humans Infant, Newborn Male Nevus, Pigmented / classification*, congenital*, pathology Skin Neoplasms / classification*, congenital*, pathology Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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