| Comparison of (51)Chromium-labeled ethylenediamine tetra-acetic acid and iohexol as blood markers for intestinal permeability testing in Beagle dogs. | |
| | |
MedLine Citation:
|
PMID: 21652237 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
(51)Chromium-labeled ethylenediamine tetra-acetic acid ((51)Cr-EDTA) is the gold standard probe for assessing intestinal permeability (IP) in dogs, but exposure to radioactivity is a disadvantage. Iohexol is a safe contrast medium commonly used for medical imaging purposes and has been successfully applied more recently for the assessment of IP in animal models and humans. This study aimed at comparing (51)Cr-EDTA and iohexol as IP blood markers in dogs. A test solution containing (51)Cr-EDTA and iohexol was administered intragastrically to seven healthy laboratory Beagle dogs, and percentage recoveries in serum were calculated. The strong linear association (correlation, r=0.76 and linear regression, y=0.03+5.04x) between (51)Cr-EDTA and iohexol supports the potential usefulness of iohexol as an IP blood marker in dogs. |
| | |
Authors:
|
Rafael Frias; Katrin Strube; Waldemar Ternes; M Carmen Collado; Thomas Spillmann; Satu Sankari; Elias Westermarck |
Related Documents
:
|
1388307 - Active and passive modulation of cutaneous red cell flux as measured by laser doppler a... 18780297 - Influence of blood flow and millimeter wave exposure on skin temperature in different t... 8117847 - Control of skin blood flow in pre- and full-term infants. 8983337 - Irradiation induced blood flow changes in the breast during radiotherapy--a pilot study. 18384647 - Permeation of blood-borne il15 across the blood-brain barrier and the effect of lps. 11597587 - Age-related changes in muscarinic cholinergic receptors in the living brain: a pet stud... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-6-6 |
Journal Detail:
|
Title: Veterinary journal (London, England : 1997) Volume: - ISSN: 1532-2971 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
|
Created Date: 2011-6-9 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9706281 Medline TA: Vet J Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Central Animal Laboratory, University of Turku, Kiinamyllynkatu 10, C6, FIN-20520 Turku, Finland; Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Finland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A systematic review of CPAP adherence across age groups: Clinical and empiric insights for developin...
Next Document: Partial characterization of cobalamin deficiency in Chinese Shar Peis.