Document Detail


Comparison of the 50 g capillary plasma glucose tolerance test with the 75 g venous plasma glucose tolerance test in pregnancy.
MedLine Citation:
PMID:  8840705     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare the 50 g oral glucose tolerance test with capillary sampling used in the Mercy Hospital for Women, Melbourne with the 75 g test with venous sampling advocated by the Australasian Diabetes in Pregnancy Society. METHODS: Both the 50 g and 75 g glucose tolerance tests were performed on 60 women. Criteria for diagnosing gestational diabetes were the combination of a 1-hour capillary plasma glucose > or = 9 mmol/l and a 2-hour glucose > or = 7 mmol/l for the 50 g test and a fasting glucose > or = 5.5 mmol/l and/or a 2-hour venous plasma glucose > or = 8.0 mmol/l for the 75 g test. RESULTS: Twenty-eight of 60 women had gestational diabetes diagnosed with the 50 g test; 24 of these, and an additional 5 had gestational diabetes diagnosed on the 75 g test. Twenty-seven women had normal results on both tests. The kappa statistic was 0.70. The 1-hour glucose value was similar for both tests, but the 2-hour value was significantly higher for the 75 g test (mean difference 0.65 mmol/l, 95% confidence limits 0.24-1.01 mmol/l, p = 0.003). The area under the curve was similar for the 2 tests. CONCLUSIONS: The 2 tests diagnose similar women as having gestational diabetes. The combination of a 75 g load and venous sampling gives similar 1-hour but higher 2-hour values than a 50 g load and capillary sampling.
Authors:
O A Henry; D C Shelley-Jones; J N Oats; P Wein; N A Beischer
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  22     ISSN:  1341-8076     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1997-02-11     Completed Date:  1997-02-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  215-9     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, University of Melbourne, Australia.
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MeSH Terms
Descriptor/Qualifier:
Diabetes, Gestational / diagnosis*
Female
Glucose Tolerance Test / methods*
Humans
Pregnancy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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