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Comparison of the 308-nm excimer laser with the 308-nm excimer lamp in the treatment of vitiligo - a randomized bilateral comparison study.
MedLine Citation:
PMID:  23281694     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Vitiligo is an acquired pigment disorder characterized by areas of depigmented skin resulting from the loss of epidermal melanocytes. Recently, several investigations have documented the benefits of excimer phototherapy (e.g., using the 308-nm excimer laser or the 308-nm excimer lamp) for the treatment of vitiligo.
AIM: To compare the effectiveness of the 308-nm excimer laser with the 308-nm excimer lamp in the treatment of vitiligo patients.
METHODS: This intervention study was designed as a randomized self-control trial. Fourteen subjects with 48 symmetrical vitiligo lesions were enrolled in this study. One lesion was treated with the 308-nm excimer laser, and its counterpart was treated with the 308-nm excimer lamp. Lesions were treated three times a week with the same dose on both sides for a total of 20 sessions.
RESULTS: All of the patients completed the study, and 48 lesions were treated. The two treatments exhibited similar results in terms of repigmentation.
CONCLUSIONS: The 308-nm excimer lamp and the 308-nm excimer laser exhibited similar efficacies in treating vitiligo.
Qiong Shi; Kai Li; Jun Fu; Yanchun Wang; Cuiling Ma; Qiang Li; Chunying Li; Tianwen Gao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Photodermatology, photoimmunology & photomedicine     Volume:  29     ISSN:  1600-0781     ISO Abbreviation:  Photodermatol Photoimmunol Photomed     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013641     Medline TA:  Photodermatol Photoimmunol Photomed     Country:  England    
Other Details:
Languages:  eng     Pagination:  27-33     Citation Subset:  IM    
Copyright Information:
© 2013 John Wiley & Sons A/S.
Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
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