Document Detail

Comparison of 30-day mortality between anterior-wall versus inferior-wall ST-segment elevation myocardial infarction complicated by cardiogenic shock in patients undergoing primary coronary angioplasty.
MedLine Citation:
PMID:  20606428     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: In this study, 30-day mortality from cardiogenic shock caused by left anterior descending artery (LAD) occlusion was compared with that caused by left circumflex (LCX) or right coronary artery (RCA) occlusion after primary percutaneous coronary intervention (PCI).
METHODS: Between May 2001 and December 2009, 212 consecutive patients with anterior-wall ST-elevation myocardial infarction complicated by cardiogenic shock due to LAD (n = 97) occlusion (group 1) and LCX or RCA (n = 115) occlusion (group 2) undergoing primary PCI were enrolled.
RESULTS: The results showed a higher mean peak level of creatine phosphokinase and incidence of extracorporeal membrane oxygenation in group 1 than group 2 (all p < 0.01). However, no significant difference was noted in the achievement of normal blood flow in the infarct-related artery (p = 0.461) and 30-day morality (p = 0.338). Univariate analysis demonstrated a significant association of 30-day morality with age, lower left-ventricular ejection fraction, advanced congestive heart failure and unsuccessful reperfusion (all p < 0.02). Multivariate analysis revealed unsuccessful reperfusion as the most independent predictor of 30-day mortality (p = 0.002).
CONCLUSION: No significant difference was noted in 30-day mortality between patients with acute myocardial infarction and cardiogenic shock caused by LAD occlusion and by either RCA or LCX occlusion undergoing primary PCI.
Tzu-Hsien Tsai; Han-Tan Chai; Cheuk-Kwan Sun; Steve Leu; Chang-Qing Fan; Ze-Hong Zhang; Hsiu-Yu Fang; Ali A Youssef; Hisham Hussein; Cheng-Hsu Yang; Chiung-Jen Wu; Hon-Kan Yip
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-07-03
Journal Detail:
Title:  Cardiology     Volume:  116     ISSN:  1421-9751     ISO Abbreviation:  Cardiology     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-10-25     Revised Date:  2012-05-07    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  144-50     Citation Subset:  IM    
Copyright Information:
Copyright 2010 S. Karger AG, Basel.
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC.
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MeSH Terms
Angioplasty, Balloon, Coronary / mortality*
Anterior Wall Myocardial Infarction* / mortality,  radiography,  therapy
Coronary Angiography
Electrocardiography / statistics & numerical data*
Logistic Models
Middle Aged
Predictive Value of Tests
Shock, Cardiogenic / mortality*,  therapy*
Comment In:
Cardiology. 2010;116(2):142-3   [PMID:  20606427 ]

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