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Comparison of 2 monocular pupillometers and an autorefractor for measurement of the dark-adapted pupil diameter.
MedLine Citation:
PMID:  21420590     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE: To compare the performance of the Marco Nidek ARK-530A autorefractor pupillometer function and the Keeler PupilScan II pupillometer (study pupillometer) against the clinical standard NeurOptics PLR-200 pupillometer (standard pupillometer) for measurement of the dark-adapted pupil diameter.
SETTING: Department of Ophthalmology and Visual Sciences, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
DESIGN: Evaluation of diagnostic test or technology.
METHODS: Subjects aged 20 to 60 years were dark-adapted for 2 minutes at 1 lux ambient illumination. Accommodation was controlled through distance fixation. The dark-adapted pupil diameter was measured with the standard pupillometer, then the study pupillometer, then the autorefractor. Results were compared using Bland-Altman graphs.
RESULTS: The autorefractor underestimated the dark-adapted pupil diameter by a mean of 1.03 mm (range 0.0 to 2.3 mm). Thirty-four (85%) measurements were at least 0.5 mm smaller than the corresponding standard pupillometer values, and 16 (40%) were more than 1.0 mm smaller. Observer experience did not improve accuracy. The study pupillometer underestimated the dark-adapted pupil diameter by a mean of 0.31 mm (range 0.0 to 0.9 mm). Ten (25%) measurements were at least 0.5 mm smaller than the standard pupillometer values. Accuracy improved in the final 10 subjects (study pupillometer smaller; mean difference 0.16 mm; range 0.0 to 0.4 mm).
CONCLUSIONS: The autorefractor pupillometry function had an unpredictable negative bias (variable underestimation of dark-adapted pupil diameter). The study pupillometer had a slight negative bias but required significant examiner skill and knowledge of normal pupil movement to obtain a valid result. Neither device was sufficiently accurate for confident surgical planning or clinical diagnosis.
FINANCIAL DISCLOSURE: Neither author has a financial or proprietary interest in any material or method mentioned.
Authors:
Sandra M Brown; Jay C Bradley
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cataract and refractive surgery     Volume:  37     ISSN:  1873-4502     ISO Abbreviation:  J Cataract Refract Surg     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8604171     Medline TA:  J Cataract Refract Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  660-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
Affiliation:
From the Department of Ophthalmology and Visual Sciences (Bradley), Texas Tech University Health Sciences Center, Lubbock, Texas, and Cabarrus Eye Center (Brown), Concord, North Carolina, USA.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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