Document Detail

Comparing exposure metrics in the relationship between PM2.5 and birth weight in California.
MedLine Citation:
PMID:  15361898     Owner:  NLM     Status:  MEDLINE    
Although studies suggest that air pollution is linked to perinatal outcomes, the geographic characterization of exposure to pollution differs between the studies. We compared neighborhood- and county-level measures of air pollution exposure, while examining the association between particulate matter less than 2.5 microm in aerodynamic diameter (PM(2.5)) and birth weight among full-term births in California in 2000. To reduce the effects of demographic variability, our analysis was limited to two populations of 8579 non-Hispanic white and 8114 Hispanic mothers who were married, between 20 and 30 years of age, completed at least a high school education, and gave birth for the first time. Measurements from the nearest monitor, and average and distance-weighted average of monitors within a 5-mile radius from each mother's residence (constituting neighborhood metrics) and the mean of monitors within each mother's county of residence were considered. PM(2.5) measurements, provided by the California Air Resources Board, were calculated to correspond to each mother's 9-month gestation period. Although metrics within the 5-mile radii and the county were highly correlated (r(2)=0.78), the county-level metric provided a stronger association between PM(2.5) and birth weight (beta=-4.04, 95% confidence interval =-6.71, -1.37) than the metric for the average of all monitors within 5-miles (beta=-1.38, 95% confidence interval =-3.36, 0.60) among non-Hispanic white mothers; similar results were observed among the Hispanic sample of mothers. Consequently, inferences from studies using different definitions of air pollution exposure may not be comparable.
Rupa Basu; Tracey J Woodruff; Jennifer D Parker; Louise Saulnier; Kenneth C Schoendorf
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of exposure analysis and environmental epidemiology     Volume:  14     ISSN:  1053-4245     ISO Abbreviation:  J Expo Anal Environ Epidemiol     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-13     Completed Date:  2005-01-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9111438     Medline TA:  J Expo Anal Environ Epidemiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  391-6     Citation Subset:  IM    
US Environmental Protection Agency, 1200 Pennsylvania Avenue NW, Washington, DC 20460, USA.
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MeSH Terms
Air Pollutants / poisoning*
Birth Weight*
California / epidemiology
Epidemiologic Studies
Geographic Information Systems*
Infant, Newborn
Particle Size
Reproducibility of Results
Terminology as Topic
Reg. No./Substance:
0/Air Pollutants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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