| Comparing exercise in Parkinson's disease--the Berlin LSVT®BIG study. | |
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MedLine Citation:
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PMID: 20669294 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Physiotherapy is widely used in Parkinson's disease (PD), but there are few controlled studies comparing active interventions. Recently, a technique named "LSVT®BIG" has been introduced. LSVT®BIG is derived from the Lee Silverman Voice Treatment and focuses on intensive exercising of high-amplitude movements. In the present comparative study, 60 patients with mild to moderate PD were randomly assigned to receive either one-to-one training (BIG), group training of Nordic Walking (WALK), or domestic nonsupervised exercises (HOME). Patients in training (BIG) and WALK received 16 hours of supervised training within 4 (BIG) or 8 (WALK) weeks. The primary efficacy measure was difference in change in Unified Parkinson's Disease Rating Scale (UPDRS) motor score from baseline to follow-up at 16 weeks between groups. UPDRS scores were obtained by blinded video rating. ANCOVA showed significant group differences for UPDRS-motor score at final assessment (P < 0.001). Mean improvement of UPDRS in BIG was -5.05 (SD 3.91) whereas there was a mild deterioration of 0.58 (SD 3.17) in WALK and of 1.68 (SD 5.95) in HOME. LSVT®BIG was also superior to WALK and HOME in timed-up-and-go and timed 10 m walking. There were no significant group differences for quality of life (PDQ39). These results provide evidence that LSVT®BIG is an effective technique to improve motor performance in patients with PD. |
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Authors:
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Georg Ebersbach; Almut Ebersbach; Daniela Edler; Olaf Kaufhold; Matthias Kusch; Andreas Kupsch; Jörg Wissel |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Movement disorders : official journal of the Movement Disorder Society Volume: 25 ISSN: 1531-8257 ISO Abbreviation: Mov. Disord. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-14 Completed Date: 2010-12-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610688 Medline TA: Mov Disord Country: United States |
Other Details:
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Languages: eng Pagination: 1902-8 Citation Subset: IM |
Copyright Information:
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© 2010 Movement Disorder Society. |
Affiliation:
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Movement Disorders Clinic, Beelitz-Heilstätten, Germany. ebersbach@parkinson-beelitz.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Analysis of Variance Exercise Therapy* Female Humans Male Middle Aged Parkinson Disease / rehabilitation* Quality of Life Treatment Outcome Walking |
| Comments/Corrections | |
Erratum In:
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Mov Disord. 2010 Oct 30;25(14):2478 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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