Document Detail

Comparing the effectiveness of Q-switched Ruby laser treatment with that of Q-switched Nd:YAG laser for oculodermal melanosis (Nevus of Ota).
MedLine Citation:
PMID:  20619756     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND AND OBJECTIVE: The objective of this study was to compare the efficacy and safety of Q-switched Ruby laser versus Q-switched neodymium:yttrium-aluminium-garnet (Nd:YAG) laser for oculodermal melanosis (Nevus of Ota) birthmarks in a large group of patients.
STUDY DESIGN/MATERIALS AND METHODS: A retrospective review was conducted of 94 patients with Nevus of Ota treated with a Q-switched Ruby laser and a Q-switched Nd:YAG laser over a 3-year period. The subjects' ages ranged from 3 to 64 years; there were 70 females and 24 males, all of whom were of Asian descent. The number of treatments ranged from 1 to 8. Duration of treatment ranged from 6 months to 3 years and 10 months, with a mean of 14 months. Patients (n=47) received Q-switched Ruby laser treatment (694nm) using light dosages of 7-10Jcm(-2). Subsequent patients (n=47) received Q-switched Nd:YAG laser treatment (1064nm) using light dosages of 7-10Jcm(-2). The primary efficacy measurement was the quantitative assessment of clearing and fading response using the DermaSpectrometer for the Q-switched Ruby laser group versus the Q-switched Nd:YAG laser group.
RESULTS: Based on a paired t-test, clinical and statistically significant differences in clearing and fading response were observed amongst the Q-switched Ruby laser-treated subjects as preferred to the appearance of Q-switched Nd:YAG laser-treated group (P<0.05). In both groups, transient hyperpigmentation resolved in all subjects within 6 months. Permanent hyperpigmentation or scarring was not observed in either group.
CONCLUSION: Use of a Q-switched Ruby laser resulted in better clearing and fading as compared with Q-switched Nd:YAG laser.
Cheng-Jen Chang; Ching-Song Kou
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Publication Detail:
Type:  Journal Article     Date:  2010-07-08
Journal Detail:
Title:  Journal of plastic, reconstructive & aesthetic surgery : JPRAS     Volume:  64     ISSN:  1878-0539     ISO Abbreviation:  J Plast Reconstr Aesthet Surg     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101264239     Medline TA:  J Plast Reconstr Aesthet Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  339-45     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
Department of Plastic Surgery, Chang Gung Memorial Hospital, Chang Gung University, 199 Tung Hwa North Road, Taipei, Taiwan.
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