Document Detail


Comparing Risk Estimates Following Diagnostic CT Radiation Exposures Employing Different Methodological Approaches.
MedLine Citation:
PMID:  24776915     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The current study has two aims: the first is to quantify the difference between radiation risks estimated with the use of organ or effective doses, particularly when planning pediatric and adult computed tomography (CT) examinations. The second aim is to determine the method of calculating organ doses and cancer risk using dose-length product (DLP) for typical routine CT examinations. In both cases, the radiation-induced cancer risks from medical CT examinations were evaluated as a function of gender and age. Lifetime attributable risk values from CT scanning were estimated with the use of ICRP (Publication 103) risk models and Russian national medical statistics data. For populations under the age of 50 y, the risk estimates based on organ doses usually are 30% higher than estimates based on effective doses. In older populations, the difference can be up to a factor of 2.5. The typical distributions of organ doses were defined for Chest Routine, Abdominal Routine, and Head Routine examinations. The distributions of organ doses were dependent on the anatomical region of scanning. The most exposed organs/tissues were thyroid, breast, esophagus, and lungs in cases of Chest Routine examination; liver, stomach, colon, ovaries, and bladder in cases of Abdominal Routine examination; and brain for Head Routine examinations. The conversion factors for calculation of typical organ doses or tissues at risk using DLP were determined. Lifetime attributable risk of cancer estimated with organ doses calculated from DLP was compared with the risk estimated on the basis of organ doses measured with the use of silicon photodiode dosimeters. The estimated difference in LAR is less than 29%.
Authors:
Valery V Kashcheev; Evgeny A Pryakhin; Alexander N Menyaylo; Sergey Yu Chekin; Viktor K Ivanov
Related Documents :
19502225 - Rational dosing of antimicrobial agents: pharmacokinetic and pharmacodynamic strategies.
23340005 - Repurposing itraconazole as a treatment for advanced prostate cancer: a noncomparative ...
23504305 - Stereotactic body radiation therapy for the primary treatment of localized prostate can...
22217885 - Intraosseous infusion is unreliable for adenosine delivery in the treatment of supraven...
17381445 - Effect of dose on the frequency of major birth defects following fetal exposure to lamo...
7844385 - Systemic immunoprophylaxis of nasal respiratory syncytial virus infection in cotton rats.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Health physics     Volume:  106     ISSN:  1538-5159     ISO Abbreviation:  Health Phys     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-04-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985093R     Medline TA:  Health Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  806-11     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  EPR Retrospective Dosimetry with Fingernails: Report on First Application Cases.
Next Document:  Characterization of h7 influenza a virus in wild and domestic birds in Korea.