| Comparing an Immediate Cessation Versus Reduction Approach to Smokeless Tobacco Cessation. | |
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MedLine Citation:
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PMID: 22218402 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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INTRODUCTION: Relatively few studies have investigated pharmacological or behavioral treatment of smokeless tobacco (ST) users who do not have immediate quit plans. In this study, we compared a reduction treatment approach with an immediate cessation approach in a population of ST users who reported no immediate plans to quit. METHODS: Subjects randomly assigned to the immediate cessation condition set a quit date soon after enrollment and were offered 2 weeks of nicotine patch therapy to help in their cessation efforts. Subjects assigned to the ST reduction group were provided with their choice of either 4 mg nicotine lozenge or ST brand switching to help them reduce their ST use or levels of nicotine exposure, respectively. Quit date was 6 weeks after the onset of treatment. Follow-up was at 12 weeks and 26 weeks postenrollment and 26 weeks postquit. RESULTS: Both 7-day point prevalence abstinence and prolonged abstinence rates following the quit date were significantly higher in the immediate cessation group versus the reduction group at 12 and 26 weeks (all p values ≤ .04) and for prolonged abstinence at 6 months postquit (p = .002). Significant reductions in ST use among nonquitters were observed for both groups (p < .0001) with no differences between groups.Conclusion:Our study demonstrated that immediate cessation with an established quit date resulted in greater cessation success than a gradual reduction approach among ST users who do not have an immediate quit plan but are motivated to quit. |
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Authors:
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Katherine R Schiller; Xianghua Luo; Amanda J Anderson; Joni A Jensen; Sharon S Allen; Dorothy K Hatsukami |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-4 |
Journal Detail:
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Title: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco Volume: - ISSN: 1469-994X ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9815751 Medline TA: Nicotine Tob Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Tobacco Research Programs, University of Minnesota, 717 Delaware Street SE, Minneapolis MN 55414, USA. hatsu001@umn.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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