| Comparing the effectiveness of TWEAK and T-ACE in determining problem drinkers in pregnancy. | |
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MedLine Citation:
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PMID: 20497951 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: The TWEAK and T-ACE screening tools are validated methods of identifying problem drinking in a pregnant population. The objective of this study was to compare the effectiveness of the TWEAK and T-ACE screening tools in identifying problem drinking using traditional cut-points (CP). METHODS: Study participants consisted of women calling the Motherisk Alcohol Helpline for information regarding their alcohol use in pregnancy. In this cohort, concerns surrounding underreporting are not likely as women self-report their alcohol consumption. Participant's self-identification, confirmed by her amount of alcohol use, determined whether she was a problem drinker or not. The TWEAK and T-ACE tools were administered on both groups and subsequent analysis was done to determine if one tool was more effective in predicting problem drinking. RESULTS: The study consisted of 75 problem and 100 non-problem drinkers. Using traditional CP, the TWEAK and T-ACE tools both performed similarly at identifying potential at-risk women (positive predictive value = 0.54), with very high sensitivity rates (100-99% and 100-93%, respectively) but poor specificity rates (36-43% and 19-34%, respectively). Upon comparison, there was no statistical difference in the effectiveness for one test performing better than next using either CP of 2 (P = 0.66) or CP of 3 (P = 0.38). CONCLUSION: Despite the lack of difference in performance, improved specificity associated with TWEAK suggests that it may be better suited to screen at-risk populations seeking advice from a helpline. |
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Authors:
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M Sarkar; T Einarson; G Koren |
Publication Detail:
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Type: Comparative Study; Journal Article Date: 2010-05-23 |
Journal Detail:
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Title: Alcohol and alcoholism (Oxford, Oxfordshire) Volume: 45 ISSN: 1464-3502 ISO Abbreviation: Alcohol Alcohol. Publication Date: 2010 Jul-Aug |
Date Detail:
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Created Date: 2010-06-23 Completed Date: 2010-10-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8310684 Medline TA: Alcohol Alcohol Country: England |
Other Details:
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Languages: eng Pagination: 356-60 Citation Subset: IM |
Affiliation:
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Division of Clinical Pharmacology and Fetal Toxicology, Hospital for Sick Children, Toronto, Canada. tsarkar@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alcoholism
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complications,
diagnosis* Cohort Studies Female Humans Interviews as Topic Pregnancy Pregnancy Complications / diagnosis* Questionnaires* Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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