Document Detail

Comparing Aortic Root Replacements: Porcine Bioroots Versus Pericardial Versus Mechanical Composite Roots: Hemodynamic and Ventricular Remodeling at Greater Than One-Year Follow-Up.
MedLine Citation:
PMID:  22884595     Owner:  NLM     Status:  Publisher    
BACKGROUND: Stentless porcine bioroots and pericardial composite roots were developed as prostheses that avoid the anticoagulation necessary for mechanical composite roots. Data on the hemodynamics of all root replacements are lacking and questions remain regarding comparative performance. METHODS: This study evaluated patients receiving a stentless porcine bioroot, a pericardial, or a mechanical composite root at a single institution from January 2000 to December 2008. All patients underwent preoperative, postoperative and greater than 1-year echocardiograms. All root replacements were performed for aortic insufficiency or aneurysm. Median follow-up was 3.3 years (1 to 8 years). RESULTS: There were no significant differences in preoperative left ventricular ejection fraction, aortic valve peak gradient, mean gradient, left ventricular end diastolic diameter, and left ventricular end systolic diameter. Postoperative peak and mean gradients in mechanical composite roots were significantly higher than stentless porcine bioroots. At greater than 1 year, stentless porcine bioroots had significantly lower peak and mean gradients than both mechanical composite roots and pericardial composite roots. The end diastolic diameter was also significantly smaller in stentless porcine bioroots at greater than 1 year than mechanical composite roots. CONCLUSIONS: All prostheses resulted in favorable hemodynamic and ventricular remodeling. Stentless porcine bioroots had the lowest gradients at greater than 1 year of all root replacements, with significantly better ventricular remodeling when compared with mechanical composite roots. Pericardial roots also had favorable hemodynamics and ventricular remodeling, suggesting that they are a viable alternative.
Fenton H McCarthy; Joseph E Bavaria; Alberto Pochettino; Zachary Fox; Patrick Moeller; Wilson Y Szeto; Nimesh D Desai
Related Documents :
19195505 - Usefulness of serum cathepsin l as an independent biomarker in patients with coronary h...
6737675 - The effects of reperfusion of infarct-related coronary artery on serum creatine phospho...
433835 - A radioimmunoassay for the measurement of human cardiac myosin light chains.
3197055 - Mechanism of myocardial injury in dogs with hypokalaemia.
10466685 - Cardiological applications of nuclear medicine.
11156075 - Double stenting for esophageal and tracheobronchial stenoses.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-9
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  -     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Department of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Gastric Motor Activity in Gastric Pull-Up Esophagectomized Patients With and Without Reflux Symptoms...
Next Document:  Primary Resection of Kommerell Diverticulum and Left Subclavian Artery Transfer.