| Comparative trial of Permethrin 5% vs. Lindane 1 % for the treatment of scabies. | |
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MedLine Citation:
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PMID: 22905702 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Objective: Treatment of scabies is an important issue in infectious dermatology. The aim of this study was to specify whether permethrin is effective for the treatment of human scabies and to compare its effectiveness with that of 1% lindane by topical application. Methods: 220 patients with scabies with the mean age of 44 ± 12/24, attending the study. Patients were divided into two groups randomly. The first group and their family contacts received 5% permethrin cream and the other received 1% lindane lotion. Treatment was evaluated at intervals of 2 and 4 weeks. Results: Of 254 patients, 220 completed the study. 110 in the group treated with lindane and 110 in the group treated with permethrin. Permethrin provided an improvement rate of 92 (83.6%) after two weeks, whereas lindane was effective only in 54 (49%) of patients. After four weeks improvement rate was 96.3% (106 of 110) in permethrin group since it was only 69.1% (76 of 110) in lindane group. Conclusion: Permethrin (5%) cream was found to be significantly more effective in the treatment of scabies in comparison with lindane in this study. There were no adverse effects with either permethrin or lindane. |
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Authors:
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Mohamad Goldust; Farideh Golforoushan; Mohamad Reza Ranjkesh; Shahla Babae Nejad; Elham Rezaee |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-21 |
Journal Detail:
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Title: The Journal of dermatological treatment Volume: - ISSN: 1471-1753 ISO Abbreviation: J Dermatolog Treat Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8918133 Medline TA: J Dermatolog Treat Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Tabriz, University of Medical sciences , Tabriz, Iran. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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