Document Detail


Comparative trends in shortening velocity and force production in skeletal muscles.
MedLine Citation:
PMID:  12121850     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Skeletal muscles are diverse in their properties, with specific contractile characteristics being matched to particular functions. In this study, published values of contractile properties for >130 diverse skeletal muscles were analyzed to detect common elements that account for variability in shortening velocity and force production. Body mass was found to be a significant predictor of shortening velocity in terrestrial and flying animals, with smaller animals possessing faster muscles. Although previous studies of terrestrial mammals revealed similar trends, the current study indicates that this pattern is more universal than previously appreciated. In contrast, shortening velocity in muscles used for swimming and nonlocomotory functions is not significantly affected by body size. Although force production is more uniform than shortening velocity, a significant correlation with shortening velocity was detected in muscles used for locomotion, with faster muscles tending to produce more force. Overall, the contractile properties of skeletal muscles are conserved among phylogenic groups, but have been significantly influenced by other factors such as body size and mode of locomotion.
Authors:
Scott Medler
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of physiology. Regulatory, integrative and comparative physiology     Volume:  283     ISSN:  0363-6119     ISO Abbreviation:  Am. J. Physiol. Regul. Integr. Comp. Physiol.     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-07-17     Completed Date:  2002-08-15     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  100901230     Medline TA:  Am J Physiol Regul Integr Comp Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  R368-78     Citation Subset:  IM; S    
Affiliation:
Department of Biology, Colorado State University, Fort Collins, Colorado 80523, USA. smedler@lamar.colostate.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Biomechanics
Body Weight / physiology*
Databases, Factual
Humans
Invertebrates
Locomotion / physiology
Muscle Contraction / physiology*
Muscle, Skeletal / physiology
Muscles / physiology*
Physiology, Comparative
Regression Analysis
Stress, Mechanical
Vertebrates
Grant Support
ID/Acronym/Agency:
1-F32-AR-08597-01A1/AR/NIAMS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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