Document Detail

Comparative tissue tolerance of a new endodontic sealer.
MedLine Citation:
PMID:  1533448     Owner:  NLM     Status:  MEDLINE    
An experimental radiopaque resin root canal sealer was tested for tissue biocompatibility in rat connective tissue. The controls were four widely used sealers: Sealapex, Kerr's sealer, AH-26, and Roth's sealer. Polyethylene tubes were filled with the sealers and allowed to set for 24 hours in 100% humidity. Each sealer was implanted in the connective tissue of Sprague-Dawley rats and removed after 3, 10, 20, 30, and 60 days, fixed, and histologically prepared for light microscope evaluation. At each time period there was practically no difference in the reaction of all the sealers. By 60 days, the total picture was one of well-tolerated biocompatibility.
D Molloy; M Goldman; R R White; S Kabani
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, and oral pathology     Volume:  73     ISSN:  0030-4220     ISO Abbreviation:  Oral Surg. Oral Med. Oral Pathol.     Publication Date:  1992 Apr 
Date Detail:
Created Date:  1992-06-04     Completed Date:  1992-06-04     Revised Date:  2010-07-05    
Medline Journal Info:
Nlm Unique ID:  0376406     Medline TA:  Oral Surg Oral Med Oral Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  490-3     Citation Subset:  D; IM    
Tufts University School of Dental Medicine, Boston, Mass.
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MeSH Terms
Biocompatible Materials / chemistry*
Bismuth / chemistry
Bisphenol A-Glycidyl Methacrylate
Calcium Hydroxide / chemistry
Connective Tissue / pathology
Contrast Media
Dental Bonding
Dental Cements / chemistry
Drug Combinations
Epoxy Resins*
Giant Cells / pathology
Granulation Tissue / pathology
Macrophages / pathology
Materials Testing
Methenamine / chemistry
Neutrophils / pathology
Polymethacrylic Acids / chemistry
Rats, Inbred Strains
Resins, Synthetic / chemistry
Root Canal Filling Materials / chemistry*
Silver / chemistry
Skin / pathology
Time Factors
Titanium / chemistry
Reg. No./Substance:
0/Biocompatible Materials; 0/Contrast Media; 0/Dental Cements; 0/Drug Combinations; 0/Epoxy Resins; 0/Polymethacrylic Acids; 0/Resins, Synthetic; 0/Root Canal Filling Materials; 0/Salicylates; 100-97-0/Methenamine; 115055-59-9/Sealapex; 1305-62-0/Calcium Hydroxide; 1565-94-2/Bisphenol A-Glycidyl Methacrylate; 55599-25-2/epoxy resin AH-26; 7440-22-4/Silver; 7440-32-6/Titanium; 7440-69-9/Bismuth

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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