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Comparative study of two collagen membranes for guided tissue regeneration therapy in periodontal intrabony defects: a randomized clinical trial.
MedLine Citation:
PMID:  25177521     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
PURPOSE: THE PURPOSE OF THIS STUDY WAS TO ASSESS AND COMPARE THE CLINICAL AND RADIOGRAPHIC OUTCOMES OF GUIDED TISSUE REGENERATION THERAPY FOR HUMAN PERIODONTAL INTRABONY DEFECTS USING TWO DIFFERENT COLLAGEN MEMBRANES: a porous nonchemical cross-linking collagen membrane (NC) and a bilayer collagen membrane (BC).
METHODS: Thirty subjects were randomly assigned and divided into the following 3 groups: a test group (NC+BM), in which a NC was used with xenograft bone mineral (BM), a positive control group (BC+BM), in which a BC was used with xenograft BM, and a negative control group (BM), in which only xenograft BM was used. The following clinical measurements were taken at baseline and 3 months after surgery: plaque index, gingival index, probing pocket depth, gingival recession, and clinical attachment level. Radiographic analysis was performed at baseline, 1 week and 3 months after surgery.
RESULTS: Membrane exposure was not observed in any cases. Significant probing depth reduction, attachment-level gain and bone fill were observed for both test and control groups compared to baseline at 3 months after surgery (P<0.05). However, there were no statistically significant differences in clinical improvement and radiographic bone fill between treatment protocols (P>0.05).
CONCLUSIONS: Within the limitations of this study, the results suggest that both NC and BC were comparable in terms of clinical and radiographic outcomes for the treatment of periodontal intrabony defects in human subjects.
Authors:
Young-Mi Chung; Jue-Yeon Lee; Seong-Nyum Jeong
Publication Detail:
Type:  Journal Article     Date:  2014-08-28
Journal Detail:
Title:  Journal of periodontal & implant science     Volume:  44     ISSN:  2093-2278     ISO Abbreviation:  J Periodontal Implant Sci     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-09-01     Completed Date:  2014-09-01     Revised Date:  2014-09-03    
Medline Journal Info:
Nlm Unique ID:  101526931     Medline TA:  J Periodontal Implant Sci     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  194-200     Citation Subset:  -    
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