| Comparative study of topical use of vasodilating solutions. | |
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MedLine Citation:
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PMID: 14582751 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Vasodilating effects of topically applied lignocaine, papaverine, and chlorpromazine were compared in rats, using a PO2 tissue perfusion monitor and histological analysis. The period of vasospasm was significantly shorter with the use of either 10% lignocaine, 2% papaverine, or 0.25% chlorpromazine than with the use of 2% lignocaine. Although our study found that no particular vasodilating agent was more effective than the others, we did find that although lignocaine 2% and 5% might not be able to fully relieve vasospasm, 10% lignocaine, 2% papaverine, or 0.25% chlorpromazine are recommended to relieve vasospasm clinically as they do not injure the arterial wall. |
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Authors:
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Kazuki Ueda; Kiyonori Harii |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Scandinavian journal of plastic and reconstructive surgery and hand surgery / Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi Volume: 37 ISSN: 0284-4311 ISO Abbreviation: Scand J Plast Reconstr Surg Hand Surg Publication Date: 2003 |
Date Detail:
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Created Date: 2003-10-29 Completed Date: 2004-02-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8707869 Medline TA: Scand J Plast Reconstr Surg Hand Surg Country: Sweden |
Other Details:
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Languages: eng Pagination: 201-7 Citation Subset: IM |
Affiliation:
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Department of Plastic and Reconstructive Surgery, Fukushima Medical University, Fukushima, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Animals Chlorpromazine / administration & dosage Female Lidocaine / administration & dosage Papaverine / administration & dosage Vascular Surgical Procedures* Vasodilator Agents / administration & dosage, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Vasodilator Agents; 137-58-6/Lidocaine; 50-53-3/Chlorpromazine; 58-74-2/Papaverine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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