Document Detail

Comparative study on rat enteromucins.
MedLine Citation:
PMID:  8403845     Owner:  NLM     Status:  MEDLINE    
1. Mucus glycoproteins (mucins) were extracted from the duodenum, small intestine (proximal and distal parts) and colon. 2. Enteromucin subunits were larger than 2 x 10(6). 3. The glycopeptides of enteromucins were essentially the same in size of the subunit. 4. The carbohydrate portion of enteromucins consisted of N-acetylgalactosamine, N-acetylglucosamine, galactose, fucose and sialic acid and the ratios of these sugars differed according to the region. 5. Average oligosaccharide length was about 8, 8, 8 and 14 sugars in the duodenum, proximal small intestine, distal small intestine and colon, respectively. 6. The proportion of threonine to serine in small intestinal mucins differed from duodenal and colonic mucins. Duodenal and colonic mucins were richer in threonine than small intestinal mucins. 7. Proximal and distal small intestinal mucins showed the same features. 8. A comparison of rat enteromucins to gastromucins indicated enteromucins to have large subunits and glycopeptides. The threonine and sialic acid content of enteromucins was higher and fucose content less compared to gastromucins.
S Ohara; K Ishihara; K Hotta
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Comparative biochemistry and physiology. B, Comparative biochemistry     Volume:  106     ISSN:  0305-0491     ISO Abbreviation:  Comp. Biochem. Physiol., B     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1993-10-22     Completed Date:  1993-10-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2984730R     Medline TA:  Comp Biochem Physiol B     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  147-52     Citation Subset:  IM    
Department of Biochemistry, School of Medicine, Kitasato University, Sagamihara, Japan.
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MeSH Terms
Acetylgalactosamine / analysis
Acetylglucosamine / analysis
Amino Acids / analysis
Carbohydrates / analysis
Colon / chemistry*
Duodenum / chemistry*
Fucose / chemistry
Galactose / analysis
Intestine, Small / chemistry*
Mucins / chemistry*
N-Acetylneuraminic Acid
Rats, Sprague-Dawley
Sialic Acids / chemistry
Reg. No./Substance:
0/Amino Acids; 0/Carbohydrates; 0/Mucins; 0/Sialic Acids; 131-48-6/N-Acetylneuraminic Acid; 26566-61-0/Galactose; 31022-50-1/Acetylgalactosamine; 3713-31-3/Fucose; 7512-17-6/Acetylglucosamine

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