| Comparative study on the properties of saturated phosphatidylethanolamine and phosphatidylcholine bilayers: barrier characteristics and susceptibility to phospholipase A2 degradation. | |
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MedLine Citation:
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PMID: 7139847 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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comparative studies on bilayer systems of saturated phosphatidylcholines and phosphatidylethanolamines revealed a maximum in ionic permeability in phosphatidylcholine bilayers at the temperature of the gel to liquid-crystalline phase transition but such an increase in permeability was not detectable in bilayers of phosphatidylethanolamine. Furthermore, it was found that at the phase transition temperature the phosphatidylcholine bilayers are subject to rapid hydrolysis by pancreatic phospholipase A2 whereas phosphatidylethanolamine bilayers are not. These differences are discussed in view of detailed information on the molecular organization in the gel and liquid crystalline phases of the two phospholipid classes. |
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Authors:
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P C Noordam; A Killian; R F Oude Elferink; J De Gier |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Chemistry and physics of lipids Volume: 31 ISSN: 0009-3084 ISO Abbreviation: Chem. Phys. Lipids Publication Date: 1982 Oct |
Date Detail:
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Created Date: 1983-01-27 Completed Date: 1983-01-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0067206 Medline TA: Chem Phys Lipids Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 191-204 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Freeze Fracturing Lipid Bilayers* Liposomes Molecular Conformation Permeability Phosphatidylcholines* / metabolism* Phosphatidylethanolamines* / metabolism Phospholipases / metabolism* Phospholipases A / metabolism* Phospholipases A2 Spectrum Analysis, Raman Surface Properties Temperature |
| Chemical | |
Reg. No./Substance:
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0/Lipid Bilayers; 0/Liposomes; 0/Phosphatidylcholines; 0/Phosphatidylethanolamines; EC 3.1.-/Phospholipases; EC 3.1.1.-/Phospholipases A; EC 3.1.1.4/Phospholipases A2 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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