Document Detail

Comparative study of polarized light propagation in biologic tissues.
MedLine Citation:
PMID:  12175278     Owner:  NLM     Status:  MEDLINE    
We report the depolarization of light scattered by a variety of birefringent and nonbirefringent tissues. We used Stokes polarimetry to investigate how scatterer structures in each tissue contribute to the depolarization of linearly versus circularly polarized light propagating through that tissue. Experiments were performed on porcine blood, fat, tendon, artery, and myocardium. The results indicate that the two incident polarization states are depolarized differently depending on the structure of the sample. As seen in sphere suspensions, for tissues containing dilute Mie scatterers, circularly polarized light is maintained preferentially over linearly polarized light. For more dense tissues, however, the reverse is true. The results illustrate situations where polarized light will provide an improvement over unpolarized light imaging, information that is crucial to optimizing existing polarimetric imaging techniques.
Vanitha Sankaran; Joseph T Walsh; Duncan J Maitland
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Publication Detail:
Type:  Comparative Study; In Vitro; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of biomedical optics     Volume:  7     ISSN:  1083-3668     ISO Abbreviation:  J Biomed Opt     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-08-14     Completed Date:  2003-02-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9605853     Medline TA:  J Biomed Opt     Country:  United States    
Other Details:
Languages:  eng     Pagination:  300-6     Citation Subset:  IM    
Beckman Laser Institute and Medical Clinic, Irvine, California 92612, USA.
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MeSH Terms
Biophysical Phenomena
Models, Biological
Optics and Photonics*
Scattering, Radiation
Sus scrofa
Grant Support
1 R01 CA85991-01/CA/NCI NIH HHS

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