Document Detail


Comparative study on the effectiveness of Coblation-assisted turbinoplasty in allergic rhinitis.
MedLine Citation:
PMID:  20502756     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To evaluate the efficacy of adding Coblation-assisted inferior turbinoplasty to a medical treatment regimen for symptoms associated with hypertrophic inferior turbinates. STUDY DESIGN/SETTING: Prospective, open-label, non-randomized trial with outpatient treatment. Patients were assigned to treatment groups in order of enrolment into the study. SUBJECTS AND METHODS: From June 2007 to June 2008, 220 patients with allergic rhinitis and hypertrophic inferior turbinates were enrolled and assigned into two groups: the surgical group who received radiofrequency thermal ablation inferior turbinoplasty and medical therapy, and the medical group who received medical therapy only. Groups were further divided into two allergen types based on antigen sensitivity: perennial and seasonal. Subjective complaints (nasal obstruction, itching, rhinorrhea, sneezing), clinical rhinoendoscopy and rhinomanometry tests results were recorded at the start of the study and 2 months post-treatment. Effect sizes for the mean improvements after treatment were tabulated for all groups. RESULTS: All study outcomes improved within all groups. Comparison between medical and surgical groups showed higher improvement in both perennial and seasonal, respectively, in nasal obstruction, sneezing, rhinomanometry, and rhinomanometry after NPT. Itching improved only in perennial allergen type. Rhinoendoscopy clinical score showed improvement in surgical group over medical group in both allergen types. CONCLUSION: Coblation-assisted turbinate reduction is a promising adjunct to medical therapy in patients with persistent symptoms associated with allergic rhinitis. Patients undergoing this surgery had greater reduction of symptoms than patients receiving medical therapy alone, where patients with perennial allergies appeared to benefit most.
Authors:
L Di Rienzo Businco; A Di Rienzo Businco; M Lauriello
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Rhinology     Volume:  48     ISSN:  0300-0729     ISO Abbreviation:  Rhinology     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-26     Completed Date:  2010-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0347242     Medline TA:  Rhinology     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  174-8     Citation Subset:  IM    
Affiliation:
Department of Otorhinolaringology, S. Eugenio Hospital-Rome, Rome, Italy. ldirienzo@businco.net
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MeSH Terms
Descriptor/Qualifier:
Ablation Techniques / methods*
Adult
Chi-Square Distribution
Endoscopy / methods
Female
Humans
Hyperostosis / complications,  surgery*
Male
Middle Aged
Nasal Obstruction / etiology,  surgery*
Prospective Studies
Rhinitis, Allergic, Perennial / complications,  surgery*
Rhinomanometry
Statistics, Nonparametric
Treatment Outcome
Turbinates / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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