Document Detail

Comparative study of dobutamine stress electron-beam computed tomography and exercise thallium scintigraphy in the diagnosis of patients with suspected coronary artery disease.
MedLine Citation:
PMID:  9559424     Owner:  NLM     Status:  MEDLINE    
To evaluate the diagnostic value of dobutamine stress electron-beam computed tomography (EBCT) as compared with exercise stress thallium-201 single-photon emission computed tomography (201T1-SPECT) for the detection of myocardial ischemia, 10 patients with proven or suspected coronary artery disease underwent both tests. Nine of the 10 patients also underwent coronary angiography. EBCT images were analyzed objectively to evaluate systolic wall thickening and analyzed segmentally to determine the distribution of the coronary arteries. Dobutamine stress EBCT revealed the presence of ischemia in 59 segments, whereas exercise stress 201T1-SPECT revealed ischemia in 51 segments (agreement = 73%). The advantage of dobutamine stress EBCT was demonstrated in the inferior/posterior segments as compared with the results of exercise stress 201T1-SPECT. The overall sensitivity for detecting ischemic regions supplied by coronary arteries with significant stenosis (diameter stenosis > 50%) was 83% for dobutamine stress EBCT and 79% for exercise stress 201T1-SPECT (p = NS), with specificities of 75% and 82% (p = NS). Thus, dobutamine stress EBCT presents a reasonable alternative to exercise stress 201T1-SPECT for the objective assessment of patients with suspected coronary artery disease.
Y Hattori; M Imazu; T Yamabe; M Yamakido; T Nakanishi; K Ito
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  62     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-06-09     Completed Date:  1998-06-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  83-90     Citation Subset:  IM    
Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
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MeSH Terms
Coronary Disease / radiography*
Exercise Test
Middle Aged
Predictive Value of Tests
Thallium Radioisotopes*
Tomography Scanners, X-Ray Computed*
Tomography, Emission-Computed, Single-Photon*
Reg. No./Substance:
0/Thallium Radioisotopes; 34368-04-2/Dobutamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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