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Comparative study of cardio-ankle vascular index between Chinese and Japanese healthy subjects.
MedLine Citation:
PMID:  24678838     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objectives: Arterial stiffness is an independent predictor for vascular diseases. Cardio-ankle vascular index (CAVI) is a new index of arterial stiffness. However, there was little research about the CAVI value between different countries. The aim of the present study was to compare CAVI between Chinese and Japanese subjects and to assess related factors. Methods: 2519 healthy persons [1245 Chinese (M/F, 524/721) and 1274 Japanese (M/F, 534/740)] from the Department of Physical Examination were enrolled into our study. CAVI was recorded using a VaseraVS-1000 vascular screening system. Results: CAVI was increasing with aging in all subjects. CAVI was significantly lower in Chinese compared with Japanese both in male and female. There was difference in lipid metabolism between these two groups. Multivariate analysis showed that age, systolic blood pressure (SBP), fasting plasma glucose (FPG), plasma creatinine (Cr) were significant independent associating factors of CAVI in Chinese persons (β = 0.548, p < 0.001; β = 0.129, p = 0.001; β = 0.105, p = 0.006; and β = 0.100, p = 0.012, respectively), whereas age, SBP, high-density lipoprotein cholesterol (HDL-C), Cr, body mass index (BMI), FPG were significant independent associating factors of CAVI in Japanese subjects (β = 0.669, p < 0.001; β = 0.198, p < 0.001; β = -0.079, p < 0.001; β = 0.090, p < 0.001; β = -0.124, p < 0.001; β = 0.055, p=0.009; respectively). Conclusions: CAVI was increasing with aging in both Chinese and Japanese subjects. CAVI was significantly lower in Chinese than in Japanese subjects. Age, SBP, FPG and creatinine were independently associated with CAVI in both Chinese and Japanese subjects.
Authors:
Hongyu Wang; Kohji Shirai; Jinbo Liu; Na Lu; Min Wang; Hongwei Zhao; Jun Xie; Xiaolan Yu; Xiaobao Fu; Hongyan Shi; Lihong Li
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-3-28
Journal Detail:
Title:  Clinical and experimental hypertension (New York, N.Y. : 1993)     Volume:  -     ISSN:  1525-6006     ISO Abbreviation:  Clin. Exp. Hypertens.     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-3-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9305929     Medline TA:  Clin Exp Hypertens     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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